Cited 4 times in
Effects of hemoglobin concentration and creatinine clearance in pro-B-type natriuretic peptide-based left ventricular filling pressure prediction in patients with preserved left ventricular systolic function.
DC Field | Value | Language |
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dc.contributor.author | 장양수 | - |
dc.contributor.author | 정남식 | - |
dc.contributor.author | 정보영 | - |
dc.contributor.author | 조승연 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 고영국 | - |
dc.contributor.author | 최의영 | - |
dc.contributor.author | 심원흠 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 임세중 | - |
dc.date.accessioned | 2015-05-19T16:36:24Z | - |
dc.date.available | 2015-05-19T16:36:24Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0002-9149 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106613 | - |
dc.description.abstract | Although N-terminal pro-B-type natriuretic peptide (pro-BNP) has been shown to correlate with left ventricular (LV) filling pressure, pro-BNP-based LV filling pressure prediction has some limitations due to several factors that affect pro-BNP. The aim of this study was to evaluate the effects of blood hemoglobin concentration and creatinine clearance (CCr) on pro-BNP-based LV filling pressure prediction in patients with preserved LV systolic function. A total of 421 consecutive patients referred for coronary angiography underwent LV pressure measurement by fluid-filled catheters. Patients with plasma creatinine levels>or=1.5 mg/dl and LV ejection fractions<50% were excluded. LV diastolic pressures and echocardiographic parameters were compared with pro-BNP levels in 281 patients. Blood hemoglobin levels and CCr were measured simultaneously. Log pro-BNP was independently correlated with hemoglobin concentration (beta=-0.261, p<0.001), CCr (beta=-0.230, p<0.001) and LV pre-A-wave pressure (beta=0.384, p<0.001). A pro-BNP level of 124 pg/ml was the optimal cutoff for LV pre-A-wave pressure>15 mm Hg in all patients (sensitivity 67%, specificity 67%, p<0.001). However, by subclassification according to hemoglobin and CCr tertiles, optimal cut-off values varied significantly, and their predictive accuracies could be improved (from 89 to 331 pg/dl, with diagnostic accuracy up to 79%). In conclusion, in the pro-BNP-based prediction of elevated LV filling pressure, subclassification on the basis of hemoglobin concentration and CCr should be considered in patients with preserved LV systolic and renal function. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 364~369 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Area Under Curve | - |
dc.subject.MESH | Creatinine/blood* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hemoglobins/analysis* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | NatriureticPeptide, Brain/physiology* | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Systole/physiology | - |
dc.subject.MESH | VentricularFunction,Left/physiology* | - |
dc.subject.MESH | VentricularPressure/physiology* | - |
dc.title | Effects of hemoglobin concentration and creatinine clearance in pro-B-type natriuretic peptide-based left ventricular filling pressure prediction in patients with preserved left ventricular systolic function. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Eui-Young Choi | - |
dc.contributor.googleauthor | Jong-Won Ha | - |
dc.contributor.googleauthor | Boyoung Joung | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Se-Joong Rim | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.contributor.googleauthor | Won-Heum Shim | - |
dc.contributor.googleauthor | Seung-Yun Cho | - |
dc.identifier.doi | 10.1016/j.amjcard.2007.08.057 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A03609 | - |
dc.contributor.localId | A03844 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A04165 | - |
dc.contributor.localId | A02202 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A03372 | - |
dc.relation.journalcode | J00071 | - |
dc.identifier.eissn | 1879-1913 | - |
dc.identifier.pmid | 18237601 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0002914907019200 | - |
dc.subject.keyword | Aged | - |
dc.subject.keyword | Area Under Curve | - |
dc.subject.keyword | Creatinine/blood* | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Hemoglobins/analysis* | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | NatriureticPeptide, Brain/physiology* | - |
dc.subject.keyword | Sensitivity and Specificity | - |
dc.subject.keyword | Systole/physiology | - |
dc.subject.keyword | VentricularFunction,Left/physiology* | - |
dc.subject.keyword | VentricularPressure/physiology* | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.alternativeName | Joung, Bo Young | - |
dc.contributor.alternativeName | Cho, Seung Yun | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.contributor.alternativeName | Shim, Won Heum | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.alternativeName | Rim, Se Joong | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Joung, Bo Young | - |
dc.contributor.affiliatedAuthor | Cho, Seung Yun | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Ko, Young Guk | - |
dc.contributor.affiliatedAuthor | Choi, Eui Young | - |
dc.contributor.affiliatedAuthor | Shim, Won Heum | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Rim, Se Joong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 101 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 364 | - |
dc.citation.endPage | 369 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF CARDIOLOGY, Vol.101(3) : 364-369, 2008 | - |
dc.identifier.rimsid | 46145 | - |
dc.type.rims | ART | - |
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