Cited 38 times in
Association between serum resistin and carotid intima media thickness in hypertension patients
DC Field | Value | Language |
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dc.contributor.author | 고영국 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 신현준 | - |
dc.contributor.author | 윤세정 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 정남식 | - |
dc.contributor.author | 최대식 | - |
dc.contributor.author | 최동훈 | - |
dc.date.accessioned | 2015-05-19T16:34:44Z | - |
dc.date.available | 2015-05-19T16:34:44Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0167-5273 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106563 | - |
dc.description.abstract | BACKGROUND: Resistin is an adipocytokine belonging to the family of cysteine rich secretory proteins. We sought to determine if a correlation between resistin levels and carotid atherosclerosis exists in hypertensive patients. METHODS: This study consisted of 307 treated hypertensive patients. Subjects were grouped into tertiles according to their resistin level. RESULTS: Carotid intima media thickness (IMT) was significantly highest in the third tertile. The first tertile had a mean carotid IMT and a mean of maximum carotid IMT of 0.63+/-0.08 and 0.81+/-0.10 mm, respectively. The 2nd tertile had measurements of 0.63+/-0.08 and 0.81+/-0.12 mm, and the 3rd tertile 0.67+/-0.12 and 0.86+/-0.11 for the same parameters. (p=0.002). Resistin levels were independently associated with the carotid IMT (mean carotid IMT: R(2)=0.159, p<0.001 and mean of maximum carotid IMT: R(2)=0.162, p<0.001) after controlling for age, gender, HDL cholesterol, triglyceride, LDL cholesterol, smoking and DM. The tertile level of resistin was significantly associated with (odds ratio=3.097, p=0.004) risk of coronary artery disease after controlling for age, gender, HDL cholesterol, triglyceride, LDL cholesterol, smoking, DM and carotid IMT. CONCLUSION: Serum resistin is independently associated with increasing carotid IMT in treated hypertensive patients | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 79~84 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adipokines/blood | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | CarotidArteries/pathology* | - |
dc.subject.MESH | CarotidArtery Diseases/blood | - |
dc.subject.MESH | CarotidArtery Diseases/pathology* | - |
dc.subject.MESH | Coronary Artery Disease/pathology | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension/blood | - |
dc.subject.MESH | Hypertension/pathology* | - |
dc.subject.MESH | Hypertension/physiopathology | - |
dc.subject.MESH | Inflammation | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Resistin/blood* | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | TunicaIntima/pathology* | - |
dc.subject.MESH | TunicaMedia/pathology* | - |
dc.title | Association between serum resistin and carotid intima media thickness in hypertension patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Hyun-Joon Shin | - |
dc.contributor.googleauthor | Sungha Park | - |
dc.contributor.googleauthor | Se-Jung Yoon | - |
dc.contributor.googleauthor | Dae Shik Choi | - |
dc.contributor.googleauthor | Deok-Kyu Cho | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.1016/j.ijcard.2007.02.028 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A00961 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A02179 | - |
dc.contributor.localId | A02569 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A04048 | - |
dc.contributor.localId | A04053 | - |
dc.relation.journalcode | J01093 | - |
dc.identifier.eissn | 1874-1754 | - |
dc.identifier.pmid | 17434634 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0167527307005189 | - |
dc.subject.keyword | Resistin | - |
dc.subject.keyword | Carotid intima media thickness | - |
dc.subject.keyword | Hypertension | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Kim, Jung Sun | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Shin, Hyun Joon | - |
dc.contributor.alternativeName | Yoon, Se Jung | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.alternativeName | Choi, Dae Sik | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Ko, Young Guk | - |
dc.contributor.affiliatedAuthor | Kim, Jung Sun | - |
dc.contributor.affiliatedAuthor | Park, Sung Ha | - |
dc.contributor.affiliatedAuthor | Shin, Hyun Joon | - |
dc.contributor.affiliatedAuthor | Yoon, Se Jung | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Choi, Dae Sik | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 125 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 79 | - |
dc.citation.endPage | 84 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol.125(1) : 79-84, 2008 | - |
dc.identifier.rimsid | 44950 | - |
dc.type.rims | ART | - |
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