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A multi-institutional study on histopathological characteristics of surgically treated renal tumors: The importance of tumor size
DC Field | Value | Language |
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dc.contributor.author | 정병하 | - |
dc.contributor.author | 최영득 | - |
dc.contributor.author | 홍성준 | - |
dc.date.accessioned | 2015-05-19T16:33:04Z | - |
dc.date.available | 2015-05-19T16:33:04Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106513 | - |
dc.description.abstract | PURPOSE: The incidence of accidentally detected small renal tumors is increasing throughout the world. In this multi-institutional study performed in Korea, histopathological characteristics of contemporarily surgically removed renal tumors were reviewed with emphasis on tumor size. MATERIALS and METHODS: Between January 1995 and May 2005, 1,702 patients with a mean age of 55 years underwent surgical treatment at 14 training hospitals in Korea for radiologically suspected malignant renal tumors. Clinicopathological factors and patient survival were analyzed. RESULTS: Of the 1,702 tumors, 91.7% were malignant and 8.3% were benign. The percentage of benign tumors was significantly greater among those < or = 4cm (13.2%) than those > 4cm (4.5%) (p < 0.001). Among renal cell carcinoma patients, the percentage of tumors classed as stage > or = T3 was significantly less among tumors < or = 4cm (5.2%) than those > 4cm (26.8%) (p < 0.001). The percentage of tumors classed as Fuhrman's nuclear grades > or = 3 was also significantly less among tumors < or = 4cm (27.3%) than tumors > 4cm (50.9%) (p < 0.001). The 5-year cancer-specific survival rate was 82.7%, and T stage (p < 0.001), N stage (p < 0.001), M stage (p = 0.025), and Fuhrman's nuclear (p < 0.001) grade were the only independent predictors of cancer-specific survival. CONCLUSION: In renal tumors, small tumor size is prognostic for favorable postsurgical histopathologies such as benign tumors, low T stages, and low Fuhrman's nuclear grades. Our observations are expected to facilitate urologists to adopt function-preserving approach in the planning of surgery for small renal tumors with favorable predicted outcomes. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 639~646 | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kidney Neoplasms/classification | - |
dc.subject.MESH | Kidney Neoplasms/pathology* | - |
dc.subject.MESH | Kidney Neoplasms/surgery* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.title | A multi-institutional study on histopathological characteristics of surgically treated renal tumors: The importance of tumor size | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨기과학) | - |
dc.contributor.googleauthor | Sun Il Kim | - |
dc.contributor.googleauthor | Yeung Deuk Choi | - |
dc.contributor.googleauthor | Se Joong Kim | - |
dc.contributor.googleauthor | Byung Ha Chung | - |
dc.contributor.googleauthor | Do Hwan Seong | - |
dc.contributor.googleauthor | Chun Il Kim | - |
dc.contributor.googleauthor | Sang Hyeon Cheon | - |
dc.contributor.googleauthor | Jin Seon Cho | - |
dc.contributor.googleauthor | Yun Seob Song | - |
dc.contributor.googleauthor | Young Sig Kim | - |
dc.contributor.googleauthor | In Rae Cho | - |
dc.contributor.googleauthor | Dong Hyeon Lee | - |
dc.contributor.googleauthor | Ki Hak Song | - |
dc.contributor.googleauthor | Hong Sup Kim | - |
dc.contributor.googleauthor | Joong Shik Lee | - |
dc.contributor.googleauthor | Won Jae Yang | - |
dc.contributor.googleauthor | Sung Joon Hong | - |
dc.identifier.doi | 10.3349/ymj.2008.49.4.639 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03607 | - |
dc.contributor.localId | A04111 | - |
dc.contributor.localId | A04402 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 18729308 | - |
dc.subject.keyword | Kidney neoplasms | - |
dc.subject.keyword | renal cell carcinoma | - |
dc.subject.keyword | nephrectomy | - |
dc.subject.keyword | surgical pathology | - |
dc.contributor.alternativeName | Chung, Byung Ha | - |
dc.contributor.alternativeName | Choi, Young Deuk | - |
dc.contributor.alternativeName | Hong, Sung Joon | - |
dc.contributor.affiliatedAuthor | Chung, Byung Ha | - |
dc.contributor.affiliatedAuthor | Choi, Young Deuk | - |
dc.contributor.affiliatedAuthor | Hong, Sung Joon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 49 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 639 | - |
dc.citation.endPage | 646 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.49(4) : 639-646, 2008 | - |
dc.identifier.rimsid | 45976 | - |
dc.type.rims | ART | - |
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