0 279

Cited 14 times in

Family history of diabetes and risk of atherosclerotic cardiovascular disease in Korean men and women

DC FieldValueLanguage
dc.contributor.author윤지은-
dc.contributor.author장양수-
dc.contributor.author지선하-
dc.date.accessioned2015-05-19T16:31:42Z-
dc.date.available2015-05-19T16:31:42Z-
dc.date.issued2008-
dc.identifier.issn0021-9150-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106472-
dc.description.abstractThe importance of family history of type 2 diabetes (FHD) as a risk factor for atherosclerotic cardiovascular disease (ASCVD) remains controversial. A report of diabetes in parents and siblings was used to establish FHD in a cohort of 1,005,230 Koreans aged 30-95 years insured by the National Health Insurance Corporation who had a biennial medical evaluation during 1992-1995. ASCVD morbidity and mortality from 1993 to 2005 were examined in relation to FHD and other ASCVD risk factors. The risk of ischemic heart disease (IHD) increased significantly (19%) in men with FHD but not in women. A strong interaction was observed between FHD and personal history of diabetes for the occurrence of ASCVD; men with both diabetes and FHD were at significantly increased risk of developing IHD, cerebrovascular disease and ASCVD with hazard ratios (HR) of 2.28, 2.07, and 2.12, respectively, compared to those who had neither FHD nor type 2 diabetes. Corresponding risks were 2.64, 2.03, and 2.10 in women, respectively. This study demonstrates that risk of ASCVD is increased among those with diabetes and a family history of diabetes; suggesting that genetic factors associated with occurrence of familial diabetes may increase risk of ASCVD beyond the risk among people without FHD-
dc.description.statementOfResponsibilityopen-
dc.format.extent224~231-
dc.relation.isPartOfATHEROSCLEROSIS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAsian Continental Ancestry Group/statistics & numerical data*-
dc.subject.MESHAtherosclerosis/ethnology*-
dc.subject.MESHCohort Studies-
dc.subject.MESHDiabetes Mellitus, Type 2/ethnology*-
dc.subject.MESHFamily Health-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRisk Factors-
dc.subject.MESHSex Distribution-
dc.titleFamily history of diabetes and risk of atherosclerotic cardiovascular disease in Korean men and women-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJi Wan Park-
dc.contributor.googleauthorJi Eun Yun-
dc.contributor.googleauthorTaesung Park-
dc.contributor.googleauthorEorin Cho-
dc.contributor.googleauthorSun Ha Jee-
dc.contributor.googleauthorYangsu Jang-
dc.contributor.googleauthorTerri H. Beaty-
dc.contributor.googleauthorJonathan M. Samet-
dc.identifier.doi10.1016/j.atherosclerosis.2007.03.037-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02608-
dc.contributor.localIdA03448-
dc.contributor.localIdA03965-
dc.relation.journalcodeJ00260-
dc.identifier.eissn1879-1484-
dc.identifier.pmid17493625-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0021915007001967-
dc.subject.keywordFamily history of diabetes-
dc.subject.keywordCardiovascular disease-
dc.subject.keywordCohort study-
dc.contributor.alternativeNameYun, Ji Eun-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameJee, Sun Ha-
dc.contributor.affiliatedAuthorYun, Ji Eun-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorJee, Sun Ha-
dc.rights.accessRightsnot free-
dc.citation.volume197-
dc.citation.number1-
dc.citation.startPage224-
dc.citation.endPage231-
dc.identifier.bibliographicCitationATHEROSCLEROSIS, Vol.197(1) : 224-231, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.