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Remifentanil prevents withdrawal movements caused by intravenous injection of rocuronium

DC FieldValueLanguage
dc.contributor.author이성진-
dc.contributor.author최병인-
dc.contributor.author최승호-
dc.contributor.author신양식-
dc.contributor.author윤경봉-
dc.contributor.author이기영-
dc.contributor.author신서경-
dc.date.accessioned2015-05-19T16:26:42Z-
dc.date.available2015-05-19T16:26:42Z-
dc.date.issued2008-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106317-
dc.description.abstractPURPOSE: The incidence of pain induced withdrawal movement following intravenous injection of rocuronium is high. This randomized, double-blind, placebo-controlled study was designed to evaluate the effect of pretreatment of remifentanil on the withdrawal movements due to intravenous injection of rocuronium during anesthetic induction. MATERIALS AND METHODS: Ninety adult female patients undergoing thyroidectomy were randomly allocated to three groups. Each patient intravenously received one of three solutions of equal volume (4 mL): normal saline (Group I, n=30), 0.5 microg/kg remifentanil (Group II, n=30) or 1 microg/kg remifentanil (Group III, n=30). Thirty seconds after remifentanil administration, anesthesia was induced with 5 mg/kg IV thiopental. Twenty seconds after thiopental injection, 0.6 mg/kg IV rocuronium was administered (injection rate of 0.5 mL/sec) and patients' withdrawal movements were assessed. Mean arterial pressure (MAP) and heart rate were assessed on arrival in the operation room, before the tracheal intubation and immediately, 1 and 2 min after the tracheal intubation. RESULTS: The incidence of withdrawal movements was significantly lower in both of the remifentanil groups (3 and 0% in Group II and III, respectively) than in the saline group (70%). Remifentanil attenuated the increase of heart rate and MAP immediately and 1 min after the tracheal intubation. CONCLUSION: The pretreatment with 0.5 and 1.0 microg/kg remifentanil of bolus doses prevented the withdrawal movements caused by rocuronium injection, and effectively blunted cardiovascular activation following tracheal intubation-
dc.description.statementOfResponsibilityopen-
dc.format.extent211~216-
dc.relation.isPartOfYonsei Medical Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleRemifentanil prevents withdrawal movements caused by intravenous injection of rocuronium-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorByung In Choi-
dc.contributor.googleauthorSeung Ho Choi-
dc.contributor.googleauthorYang-Sik Shin-
dc.contributor.googleauthorSung Jin Lee-
dc.contributor.googleauthorKyung Bong Yoon-
dc.contributor.googleauthorSeo Kyung Shin-
dc.contributor.googleauthorKi-Young Lee-
dc.identifier.doi10.3349/ymj.2008.49.2.211-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02872-
dc.contributor.localIdA04060-
dc.contributor.localIdA02123-
dc.contributor.localIdA02539-
dc.contributor.localIdA02695-
dc.contributor.localIdA04101-
dc.contributor.localIdA02109-
dc.relation.journalcodeJ02813-
dc.contributor.alternativeNameLee, Sung Jin-
dc.contributor.alternativeNameChoi, Byung In-
dc.contributor.alternativeNameChoi, Seung Ho-
dc.contributor.alternativeNameShin, Yang Sik-
dc.contributor.alternativeNameYoon, Kyoung Bong-
dc.contributor.alternativeNameLee, Ki Young-
dc.contributor.affiliatedAuthorLee, Sung Jin-
dc.contributor.affiliatedAuthorChoi, Byung In-
dc.contributor.affiliatedAuthorShin, Yang Sik-
dc.contributor.affiliatedAuthorYoon, Kyoung Bong-
dc.contributor.affiliatedAuthorLee, Ki Young-
dc.contributor.affiliatedAuthorChoi, Seung Ho-
dc.rights.accessRightsfree-
dc.citation.volume49-
dc.citation.number2-
dc.citation.startPage211-
dc.citation.endPage216-
dc.identifier.bibliographicCitationYonsei Medical Journal, Vol.49(2) : 211-216, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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