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Usefulness of 18F-fluorodeoxyglucose positron emission tomography in differential diagnosis and staging of cholangiocarcinomas

DC FieldValueLanguage
dc.contributor.author정재복-
dc.contributor.author문창모-
dc.contributor.author박승우-
dc.contributor.author방승민-
dc.contributor.author송시영-
dc.contributor.author윤미진-
dc.contributor.author이종두-
dc.date.accessioned2015-05-19T16:26:03Z-
dc.date.available2015-05-19T16:26:03Z-
dc.date.issued2008-
dc.identifier.issn0815-9319-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106297-
dc.description.abstractBACKGROUND AND AIM: (18)F-Fluoro-2-deoxy-d-glucose positron emission tomography ((18)FDG-PET) is promising for diagnosis and treatment of various malignancies. The aim of this study was to evaluate the clinical usefulness of (18)FDG-PET in differential diagnosis and staging of cholangiocarcinomas according to the intrahepatic, perihilar and common bile duct lesions and to compare with computerized tomography (CT) scan. METHODS: From January 2000 to September 2003, 54 patients with suspected cholangiocarcinoma underwent abdominal CT scan and (18)FDG-PET within a 2-week period. The PET images were analyzed visually and semiquantitatively. RESULTS: The overall accuracy of (18)FDG-PET for discriminating malignant diseases of bile duct from benign conditions was slightly higher than that of CT scan (88.9% vs 81.5%). The sensitivity of (18)FDG-PET in perihilar cholangiocarcinoma was lower than the value of intrahepatic and common bile duct cancers (83.3% vs 91.3%, 90.9%); moreover, in cases of perihilar cancer, the sensitivity of (18)FDG-PET was lower than that of CT scans (83.3% vs 91.7%). (18)FDG-PET detected nine distant metastatic lesions not found by other imaging studies and excluded two patients who potentially had resectable condition in other imaging studies from unnecessary laparotomy. CONCLUSION: The clinical usefulness of (18)FDG-PET in differential diagnosis of bile duct cancers is related to the site of primary disease. Although it is a helpful method for differential diagnosis especially in cases of intrahepatic and common bile duct cancers, (18)FDG-PET can not provide confirmative clues in perihilar cholangiocarcinoma. (18)FDG-PET may hold promise in the detection of hidden distant metastasis and can play an additional role in the evaluation of resectability. (18)FDG-PET can be complementary to CT scan in diagnosing and staging of cholangiocarcinoma-
dc.description.statementOfResponsibilityopen-
dc.format.extent759~765-
dc.relation.isPartOfJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBile Duct Neoplasms/diagnostic imaging*-
dc.subject.MESHBile Duct Neoplasms/pathology*-
dc.subject.MESHBile Ducts, Intrahepatic*-
dc.subject.MESHCholangiocarcinoma/diagnostic imaging*-
dc.subject.MESHCholangiocarcinoma/pathology*-
dc.subject.MESHDiagnosis, Differential-
dc.subject.MESHFemale-
dc.subject.MESHFluorodeoxyglucose F18*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPositron-Emission Tomography*-
dc.subject.MESHRadiopharmaceuticals*-
dc.subject.MESHRetrospective Studies-
dc.titleUsefulness of 18F-fluorodeoxyglucose positron emission tomography in differential diagnosis and staging of cholangiocarcinomas-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorChang Mo Moon-
dc.contributor.googleauthorSeungmin Bang-
dc.contributor.googleauthorJae Bock Chung-
dc.contributor.googleauthorSeung Woo Park-
dc.contributor.googleauthorSi Young Song-
dc.contributor.googleauthorMijin Yun-
dc.contributor.googleauthorJong Doo Lee-
dc.identifier.doi10.1111/j.1440-1746.2007.05173.x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03706-
dc.contributor.localIdA01390-
dc.contributor.localIdA01551-
dc.contributor.localIdA01786-
dc.contributor.localIdA02035-
dc.contributor.localIdA02550-
dc.contributor.localIdA03138-
dc.relation.journalcodeJ01417-
dc.identifier.eissn1440-1746-
dc.identifier.pmid17931372-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/j.1440-1746.2007.05173.x/abstract-
dc.subject.keywordcholangiocarcinoma-
dc.subject.keywordcomputed tomography-
dc.subject.keywordpositron emission tomography-
dc.contributor.alternativeNameChung, Jae Bock-
dc.contributor.alternativeNameMoon, Chang Mo-
dc.contributor.alternativeNamePark, Seung Woo-
dc.contributor.alternativeNameBang, Seung Min-
dc.contributor.alternativeNameSong, Si Young-
dc.contributor.alternativeNameYun, Mi Jin-
dc.contributor.alternativeNameLee, Jong Doo-
dc.contributor.affiliatedAuthorChung, Jae Bock-
dc.contributor.affiliatedAuthorMoon, Chang Mo-
dc.contributor.affiliatedAuthorPark, Seung Woo-
dc.contributor.affiliatedAuthorBang, Seung Min-
dc.contributor.affiliatedAuthorSong, Si Young-
dc.contributor.affiliatedAuthorYun, Mi Jin-
dc.contributor.affiliatedAuthorLee, Jong Doo-
dc.rights.accessRightsnot free-
dc.citation.volume23-
dc.citation.number5-
dc.citation.startPage759-
dc.citation.endPage765-
dc.identifier.bibliographicCitationJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.23(5) : 759-765, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

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