Cited 47 times in
Topical glycopyrrolate for patients with facial hyperhidrosis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤덕미 | - |
dc.contributor.author | 길혜금 | - |
dc.contributor.author | 김원옥 | - |
dc.contributor.author | 윤경봉 | - |
dc.date.accessioned | 2015-05-19T16:25:45Z | - |
dc.date.available | 2015-05-19T16:25:45Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0007-0963 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106288 | - |
dc.description.abstract | BACKGROUND: Facial hyperhidrosis may negatively impact the quality of life. Although various conservative modalities have been suggested, the condition is not often treated successfully. OBJECTIVES: To examine whether topical glycopyrrolate could be an effective and safe treatment for facial hyperhidrosis. METHODS: Twenty-five patients with facial hyperhidrosis were enrolled and treated with 2% topical glycopyrrolate on one half of the forehead while the other half of the forehead was treated with a placebo. RESULTS: The sweat production rate of the half of the forehead treated with topical glycopyrrolate was significantly reduced to 37.6+/-2.8 mg min(-1) (mean+/-SEM) compared with 102.2+/-5.5 mg min(-1) at the placebo-treated half of the forehead (P<0.001). Patients evaluated their degree of anhidrosis as excellent in six (24%) patients, good in 16 (64%), fair in two (8%) and poor in one (4%). Twenty-four patients (96%) were partially or fully satisfied with their fair to excellent anhidrosis; only one patient (who developed a transient headache after treatment) was dissatisfied with its therapeutic effect. Only seven patients (28%) experienced recurrence within 1 day while 17 patients (68%) had recurrence within 2 days. One patient (4%) remained stable for up to 4 days. CONCLUSIONS: Topical glycopyrrolate application appears to be effective and safe for the treatment of excessive facial sweating in primary craniofacial and secondary gustatory hyperhidrosis following sympathectomy. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1094~1097 | - |
dc.relation.isPartOf | BRITISH JOURNAL OF DERMATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Administration, Topical | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Cholinergic Antagonists/therapeutic use* | - |
dc.subject.MESH | Facial Dermatoses/drug therapy* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glycopyrrolate/therapeutic use* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hyperhidrosis/drug therapy* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Sweating/drug effects | - |
dc.title | Topical glycopyrrolate for patients with facial hyperhidrosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | W.O. Kim | - |
dc.contributor.googleauthor | H.K. Kil | - |
dc.contributor.googleauthor | K.B. Yoon | - |
dc.contributor.googleauthor | D.M. Yoon | - |
dc.identifier.doi | 10.1111/j.1365-2133.2008.08476.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02545 | - |
dc.contributor.localId | A00283 | - |
dc.contributor.localId | A00766 | - |
dc.contributor.localId | A02539 | - |
dc.relation.journalcode | J00408 | - |
dc.identifier.eissn | 1365-2133 | - |
dc.identifier.pmid | 18294315 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.2008.08476.x/abstract | - |
dc.subject.keyword | craniofacial | - |
dc.subject.keyword | forehead hyperhidrosis | - |
dc.subject.keyword | gustatory | - |
dc.subject.keyword | topical glycopyrrolate | - |
dc.contributor.alternativeName | Yoon, Duck Mi | - |
dc.contributor.alternativeName | Kil, Hae Keum | - |
dc.contributor.alternativeName | Kim, Won Oak | - |
dc.contributor.alternativeName | Yoon, Kyoung Bong | - |
dc.contributor.affiliatedAuthor | Yoon, Duck Mi | - |
dc.contributor.affiliatedAuthor | Kil, Hae Keum | - |
dc.contributor.affiliatedAuthor | Kim, Won Oak | - |
dc.contributor.affiliatedAuthor | Yoon, Kyoung Bong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 158 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1094 | - |
dc.citation.endPage | 1097 | - |
dc.identifier.bibliographicCitation | BRITISH JOURNAL OF DERMATOLOGY, Vol.158(5) : 1094-1097, 2008 | - |
dc.identifier.rimsid | 56329 | - |
dc.type.rims | ART | - |
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