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Exaggerated blood pressure response to exercise is associated with augmented rise of angiotensin II during exercise
DC Field | Value | Language |
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dc.contributor.author | 최의영 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 심지영 | - |
dc.contributor.author | 임세중 | - |
dc.contributor.author | 정남식 | - |
dc.contributor.author | 최동훈 | - |
dc.date.accessioned | 2015-05-19T16:22:39Z | - |
dc.date.available | 2015-05-19T16:22:39Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0735-1097 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106194 | - |
dc.description.abstract | OBJECTIVES: The aim of this study was to investigate the association between an exaggerated blood pressure (BP) response to exercise and augmented angiotensin (Ang) II rise during exercise. BACKGROUND: Although a central pressor effect of Ang II has been implicated in the pathogenesis of hypertension, the relationship between Ang II and exaggerated BP response to exercise is unclear. METHODS: Thirty-six subjects with an exaggerated BP response to exercise (18 men, age 50 +/- 16 years, Group II) were compared with 36 age- and gender-matched control subjects (18 men, age 50 +/- 16 years, Group I) with normal BP reactivity. The subjects who had resting BP >or=140/90 mm Hg or were treated with any antihypertensive drugs were excluded. The blood was sampled at rest and immediately after peak exercise for measurement of renin, Ang II, aldosterone, and catecholamine. RESULTS: At rest, there were no significant differences in BP, renin, aldosterone, and catecholamine levels between the 2 groups. The renin, aldosterone, and catecholamine were increased during exercise, but there were no significant differences between the groups. However, log Ang II at rest (0.78 +/- 0.32 vs. 0.98 +/- 0.38, p = 0.004) and peak exercise (0.84 +/- 0.35 vs. 1.17 +/- 0.51, p < 0.001) and the magnitude of the increment of log Ang II with exercise (0.06 +/- 0.12 vs. 0.19 +/- 0.20, p = 0.003) were significantly higher in the exaggerated BP response group.CONCLUSIONS: An exaggerated BP response to exercise was associated with augmented rise of Ang II during exercise. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 287~292 | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Exaggerated blood pressure response to exercise is associated with augmented rise of angiotensin II during exercise | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Chi Young Shim | - |
dc.contributor.googleauthor | Jong-Won Ha | - |
dc.contributor.googleauthor | Sungha Park | - |
dc.contributor.googleauthor | Eui-Young Choi | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Se-Joong Rim | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.1016/j.jacc.2008.03.052 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04165 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A02213 | - |
dc.contributor.localId | A03372 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A04053 | - |
dc.relation.journalcode | J01770 | - |
dc.identifier.eissn | 1558-3597 | - |
dc.identifier.pmid | angiotensin II ; catecholamine ; blood pressure ; exercise. | - |
dc.subject.keyword | angiotensin II | - |
dc.subject.keyword | catecholamine | - |
dc.subject.keyword | blood pressure | - |
dc.subject.keyword | exercise. | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Shim, Chi Young | - |
dc.contributor.alternativeName | Rim, Se Joong | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Eui Young | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Park, Sung Ha | - |
dc.contributor.affiliatedAuthor | Shim, Chi Young | - |
dc.contributor.affiliatedAuthor | Rim, Se Joong | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 52 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 287 | - |
dc.citation.endPage | 292 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol.52(4) : 287-292, 2008 | - |
dc.identifier.rimsid | 54788 | - |
dc.type.rims | ART | - |
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