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Preceding orbital granulocytic sarcoma in an adult patient with acute myelogenous leukemia with t(8;21): a case study and review of the literature.

DC Field Value Language
dc.contributor.author박용정-
dc.contributor.author박태성-
dc.contributor.author송재우-
dc.contributor.author양우익-
dc.contributor.author이경아-
dc.contributor.author정주원-
dc.contributor.author최종락-
dc.contributor.author이상국-
dc.date.accessioned2015-05-19T16:22:05Z-
dc.date.available2015-05-19T16:22:05Z-
dc.date.issued2008-
dc.identifier.issn0165-4608-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106177-
dc.description.abstractA 25-year old man with a 30 month history of proptosis and pain of the right eye was referred to Severance Hospital of Yonsei University. Orbital computed tomography (CT) demonstrated a huge mass in the right retrobulbar orbit; an incisional biopsy and orbitotomy were performed for diagnosis and orbital soft tissue decompression. Subsequent histopathology disclosed sheets of mononuclear cells in the orbital mass, and immunohistochemical stains demonstrated positive results for myeloperoxidase and CD43, which supported the diagnosis of granulocytic sarcoma (GS). After his 1-year follow-up, the patient presented with pancytopenia, and an ensuing bone marrow aspiration revealed markedly hypercellular marrow replaced by many large abnormal myeloblasts. The patient was diagnosed with acute myelogenous leukemia with t(8;21) preceded by orbital GS. Orbital GS is primarily a disease of children, and extremely rare in adults. To the best of our knowledge, only four cases of this disease in adults have been reported in the literature. Our case is the first report of preceding orbital GS in an adult patient with a complex karyotype including t(8;21).-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfCANCER GENETICS AND CYTOGENETICS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHChromosome Banding-
dc.subject.MESHChromosomes, Human, Pair 21*-
dc.subject.MESHChromosomes, Human, Pair 8*-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHImmunohistochemistry-
dc.subject.MESHKaryotyping-
dc.subject.MESHLeukemia, Myeloid, Acute/genetics*-
dc.subject.MESHLeukemia, Myeloid, Acute/therapy-
dc.subject.MESHMale-
dc.subject.MESHOrbital Neoplasms/diagnosis-
dc.subject.MESHOrbital Neoplasms/diagnostic imaging-
dc.subject.MESHOrbital Neoplasms/pathology*-
dc.subject.MESHOrbital Neoplasms/surgery-
dc.subject.MESHRadiography-
dc.subject.MESHRemission Induction-
dc.subject.MESHSarcoma, Myeloid/diagnosis-
dc.subject.MESHSarcoma, Myeloid/diagnostic imaging-
dc.subject.MESHSarcoma, Myeloid/pathology*-
dc.subject.MESHSarcoma, Myeloid/surgery-
dc.subject.MESHTime Factors-
dc.subject.MESHTranslocation, Genetic*-
dc.titlePreceding orbital granulocytic sarcoma in an adult patient with acute myelogenous leukemia with t(8;21): a case study and review of the literature.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSang-Guk Lee-
dc.contributor.googleauthorTae Sung Park-
dc.contributor.googleauthorJune-Won Cheong-
dc.contributor.googleauthorWoo Ick Yang-
dc.contributor.googleauthorJaewoo Song-
dc.contributor.googleauthorKyung-A Lee-
dc.contributor.googleauthorJuwon Kim-
dc.contributor.googleauthorYongjung Park-
dc.contributor.googleauthorJong Rak Choi-
dc.identifier.doi10.1016/j.cancergencyto.2008.04.016-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01582-
dc.contributor.localIdA01725-
dc.contributor.localIdA02054-
dc.contributor.localIdA02300-
dc.contributor.localIdA02647-
dc.contributor.localIdA03726-
dc.contributor.localIdA04182-
dc.relation.journalcodeJ00443-
dc.identifier.eissn1873-4456-
dc.identifier.pmid18656695-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0165460808002720-
dc.subject.keywordAdult-
dc.subject.keywordChromosome Banding-
dc.subject.keywordChromosomes, Human, Pair 21*-
dc.subject.keywordChromosomes, Human, Pair 8*-
dc.subject.keywordFollow-Up Studies-
dc.subject.keywordHumans-
dc.subject.keywordImmunohistochemistry-
dc.subject.keywordKaryotyping-
dc.subject.keywordLeukemia, Myeloid, Acute/genetics*-
dc.subject.keywordLeukemia, Myeloid, Acute/therapy-
dc.subject.keywordMale-
dc.subject.keywordOrbital Neoplasms/diagnosis-
dc.subject.keywordOrbital Neoplasms/diagnostic imaging-
dc.subject.keywordOrbital Neoplasms/pathology*-
dc.subject.keywordOrbital Neoplasms/surgery-
dc.subject.keywordRadiography-
dc.subject.keywordRemission Induction-
dc.subject.keywordSarcoma, Myeloid/diagnosis-
dc.subject.keywordSarcoma, Myeloid/diagnostic imaging-
dc.subject.keywordSarcoma, Myeloid/pathology*-
dc.subject.keywordSarcoma, Myeloid/surgery-
dc.subject.keywordTime Factors-
dc.subject.keywordTranslocation, Genetic*-
dc.contributor.alternativeNamePark, Yong Jung-
dc.contributor.alternativeNamePark, Tae Sung-
dc.contributor.alternativeNameSong, Jae Woo-
dc.contributor.alternativeNameYang, Woo Ick-
dc.contributor.alternativeNameLee, Kyung A-
dc.contributor.alternativeNameChung, Joo Won-
dc.contributor.alternativeNameChoi, Jong Rak-
dc.contributor.affiliatedAuthorPark, Yong Jung-
dc.contributor.affiliatedAuthorPark, Tae Sung-
dc.contributor.affiliatedAuthorSong, Jae Woo-
dc.contributor.affiliatedAuthorYang, Woo Ick-
dc.contributor.affiliatedAuthorLee, Kyung A-
dc.contributor.affiliatedAuthorChung, Joo Won-
dc.contributor.affiliatedAuthorChoi, Jong Rak-
dc.rights.accessRightsnot free-
dc.citation.volume185-
dc.citation.number1-
dc.citation.startPage51-
dc.citation.endPage54-
dc.identifier.bibliographicCitationCANCER GENETICS AND CYTOGENETICS , Vol.185(1) : 51-54, 2008-
dc.identifier.rimsid54775-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

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