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척추 수술 후 오심 및 구토의 고위험군 환자에서 Ramosetron과 Ondansetron의 효과 비교
DC Field | Value | Language |
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dc.contributor.author | 곽영란 | - |
dc.contributor.author | 박윤곤 | - |
dc.contributor.author | 심재광 | - |
dc.contributor.author | 최용선 | - |
dc.date.accessioned | 2015-05-19T16:20:44Z | - |
dc.date.available | 2015-05-19T16:20:44Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106136 | - |
dc.description.abstract | Background: Opioid based patient-controlled analgesia (PCA) effectively provides adequate pain control after spine surgery, often at the expense of high incidence of postoperative nausea and vomiting (PONV). This study was designed to compare the effect of ramosetron with ondansetron for preventing PONV in highly susceptible patients using PCA following spine surgery under general anesthesia. Methods: Seventy female patients, aged 18 to 65, scheduled for elective lumbar spine surgery, were randomly allocated into either ondansetron group (Group O, n = 35) or ramosetron group (Group R, n = 35). In patients assigned to group O, ondansetron 4 mg was injected and 12 mg was added to the PCA regimen. In patients assigned to group R, ramosetron 0.3 mg was injected and 0.3mg was added to the PCA regimen. The PCA regimen consisted of fentanyl 25μg/kg (total volume including saline: 100 ml) and was programmed to deliver 2 ml/hr as background infusion and 0.5 ml per demand with a 15 min lockout. The incidence and severity of PONV, pain score, total amount of administered rescue analgesic and rescue antiemetic were assessed following 48 hrs after surgery. Results: The incidence of PONV showed no significant differences between groups during 48 hrs after surgery. There were no differences in the severity of nausea, pain score, total amount of administered rescue analgesic and rescue antiemetic between groups. Conclusions: Ramosetron prophylaxis for preventing PONV is as effective as ondansetron in highly susceptible patients using fentanyl based PCA following spine surgery under general anesthesia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 171~175 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF ANESTHESIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 척추 수술 후 오심 및 구토의 고위험군 환자에서 Ramosetron과 Ondansetron의 효과 비교 | - |
dc.title.alternative | Comparison of ramosetron and ondansetron for preventing postoperative nausea and vomiting following spine surgery in highly susceptible patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | 양소영 | - |
dc.contributor.googleauthor | 최용선 | - |
dc.contributor.googleauthor | 심재광 | - |
dc.contributor.googleauthor | 박윤곤 | - |
dc.contributor.googleauthor | 곽영란 | - |
dc.identifier.doi | 10.4097/kjae.2008.55.2.171 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00172 | - |
dc.contributor.localId | A01593 | - |
dc.contributor.localId | A02205 | - |
dc.contributor.localId | A04119 | - |
dc.relation.journalcode | J03189 | - |
dc.identifier.eissn | 2005-7563 | - |
dc.identifier.pmid | ondansetron ; postoperative nausea and vomiting ; ramosetron. | - |
dc.subject.keyword | ondansetron | - |
dc.subject.keyword | postoperative nausea and vomiting | - |
dc.subject.keyword | ramosetron. | - |
dc.contributor.alternativeName | Kwak, Young Lan | - |
dc.contributor.alternativeName | Park, Wyun Kon | - |
dc.contributor.alternativeName | Shim, Jae Kwang | - |
dc.contributor.alternativeName | Choi, Yong Seon | - |
dc.contributor.affiliatedAuthor | Kwak, Young Lan | - |
dc.contributor.affiliatedAuthor | Park, Wyun Kon | - |
dc.contributor.affiliatedAuthor | Shim, Jae Kwang | - |
dc.contributor.affiliatedAuthor | Choi, Yong Seon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 55 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 171 | - |
dc.citation.endPage | 175 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.55(2) : 171-175, 2008 | - |
dc.identifier.rimsid | 54744 | - |
dc.type.rims | ART | - |
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