Cited 63 times in
Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study
DC Field | Value | Language |
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dc.contributor.author | 김영태 | - |
dc.date.accessioned | 2015-04-24T17:45:00Z | - |
dc.date.available | 2015-04-24T17:45:00Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0001-5792 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105996 | - |
dc.description.abstract | BACKGROUND: The aim of this study was to compare the efficacy, safety and achievement of the target hemoglobin level (Hb >or=10 g/dl) in patients with preoperative anemia due to menorrhagia who received intravenous iron sucrose compared with oral iron protein succinylate for anemia management. METHODS: Seventy-six patients with Hb levels <9.0 g/dl who were scheduled to undergo surgical treatment were randomized to receive either intravenous iron sucrose (based on the calculated total iron deficit divided into 2 ampoule infusions intravenously 3 times a week, beginning 3 weeks before surgery) or oral iron (80 mg/day of oral iron protein succinylate daily). RESULTS: The intravenous iron group had higher increases in Hb (3.0 vs. 0.8 g/dl; p < 0.0001) and ferritin levels (170.1 vs. 4.1 microg/l; p < 0.0001) than the oral iron group. Achieving the target Hb was also higher in the intravenous iron group than in the oral iron group (76.7 vs. 11.5%; p < 0.0001). There were tolerable adverse events in both groups. CONCLUSION: Preoperative intravenous iron sucrose administration is more effective than oral iron and is as safe as oral iron therapy in the correction of preoperative anemia due to menorrhagia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 37~41 | - |
dc.relation.isPartOf | ACTA HAEMATOLOGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Administration, Oral | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Anemia/blood | - |
dc.subject.MESH | Anemia/therapy* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Ferric Compounds/administration & dosage* | - |
dc.subject.MESH | Ferritins/blood | - |
dc.subject.MESH | Glucaric Acid | - |
dc.subject.MESH | Hematinics/administration & dosage* | - |
dc.subject.MESH | Hemoglobins/analysis | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infusions, Intravenous | - |
dc.subject.MESH | Menorrhagia/blood | - |
dc.subject.MESH | Menorrhagia/therapy* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Preoperative Care* | - |
dc.subject.MESH | Prospective Studies | - |
dc.title | Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology (산부인과학) | - |
dc.contributor.googleauthor | Yun Hwan Kim | - |
dc.contributor.googleauthor | Hyun Hoon Chung | - |
dc.contributor.googleauthor | Soon-Beom Kang | - |
dc.contributor.googleauthor | Seung Cheol Kim | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.identifier.doi | 10.1159/000210062 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00729 | - |
dc.relation.journalcode | J00014 | - |
dc.identifier.eissn | 1421-9662 | - |
dc.identifier.pmid | 19332985 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/210062 | - |
dc.subject.keyword | Intravenous iron therapy | - |
dc.subject.keyword | Iron deficiency anemia | - |
dc.subject.keyword | Menorrhagia | - |
dc.subject.keyword | Oral iron | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | Kim, Young Tae | - |
dc.citation.volume | 121 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 37 | - |
dc.citation.endPage | 41 | - |
dc.identifier.bibliographicCitation | ACTA HAEMATOLOGICA, Vol.121(1) : 37-41, 2009 | - |
dc.identifier.rimsid | 51501 | - |
dc.type.rims | ART | - |
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