Cited 45 times in
Clinical features and prognosis of spontaneous bacterial peritonitis in korean patients with liver cirrhosis: a multicenter retrospective study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안상훈 | - |
dc.contributor.author | 한광협 | - |
dc.contributor.author | 박준용 | - |
dc.date.accessioned | 2015-04-24T17:42:30Z | - |
dc.date.available | 2015-04-24T17:42:30Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105916 | - |
dc.description.abstract | BACKGROUND/AIMS: Although early recognition and treatment with effective antibiotics have lead to improvements in the prognosis of patients with spontaneous bacterial peritonitis (SBP), it remains to be a serious complication in cirrhotic patients. This study was designed to evaluate the clinical manifestations and prognosis of patients with liver cirrhosis and SBP in Korea. METHODS: This was a multicenter retrospective study examining 157 episodes of SBP in 145 patients with cirrhosis. SBP was diagnosed based on a polymorphonuclear cell count in ascitic fluid of >250 cells/mm(3) in the absence of data compatible with secondary peritonitis. RESULTS: The mean age of the cohort was 56 years, and 121 (77%) of the 157 episodes of SBP occurred in men. Microorganisms were isolated in 66 episodes (42%): Gram-negative bacteria in 54 (81.8%), Gram-positive in 11 (16.7%), and Candida in 1. Isolated Gram-negative organisms were resistant to third-generation cephalosporin in 6 cases (17%), to ciprofloxacin in 11 (20.8%), and to penicillin in 33 (62.3%). The treatment failure and in-hospital mortality rates were 12.1% and 21%, respectively. A high Model of End-Stage Liver Disease (MELD) score, SBP caused by extended-spectrum beta-lactamase-producing organisms, and hepatocellular carcinoma were independent prognostic factors of high in-hospital mortality. CONCLUSIONS: SBP remains to be a serious complication with high in-hospital mortality, especially in patients with a high MELD score. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 197~204 | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Clinical features and prognosis of spontaneous bacterial peritonitis in korean patients with liver cirrhosis: a multicenter retrospective study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jeong Heo | - |
dc.contributor.googleauthor | Yeon Seok Seo | - |
dc.contributor.googleauthor | Hyung Joon Yim | - |
dc.contributor.googleauthor | Taeho Hahn | - |
dc.contributor.googleauthor | Sang Hoon Park | - |
dc.contributor.googleauthor | Sang Hoon Ahn | - |
dc.contributor.googleauthor | Jun Yong Park | - |
dc.contributor.googleauthor | Ji Young Park | - |
dc.contributor.googleauthor | Moon Young Kim | - |
dc.contributor.googleauthor | Sung Keun Park | - |
dc.contributor.googleauthor | Mong Cho | - |
dc.contributor.googleauthor | Soon Ho Um | - |
dc.contributor.googleauthor | Kwang Hyub Han | - |
dc.contributor.googleauthor | Hong Soo Kim | - |
dc.contributor.googleauthor | Soon Koo Baik | - |
dc.contributor.googleauthor | Byung Ik Kim | - |
dc.contributor.googleauthor | Se Hyun Cho | - |
dc.identifier.doi | 10.5009/gnl.2009.3.3.197 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02226 | - |
dc.contributor.localId | A04268 | - |
dc.contributor.localId | A01675 | - |
dc.relation.journalcode | J00954 | - |
dc.identifier.eissn | 2005-1212 | - |
dc.identifier.pmid | 20431746 | - |
dc.subject.keyword | Liver cirrhosis | - |
dc.subject.keyword | Peritonitis | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Resistance | - |
dc.contributor.alternativeName | Ahn, Sang Hoon | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.alternativeName | Park, Jun Yong | - |
dc.contributor.affiliatedAuthor | Ahn, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Park, Jun Yong | - |
dc.citation.volume | 3 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 197 | - |
dc.citation.endPage | 204 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, Vol.3(3) : 197-204, 2009 | - |
dc.identifier.rimsid | 51437 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.