Cited 65 times in
Ischemic heart diseases: current treatments and future
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 황기철 | - |
dc.date.accessioned | 2015-04-24T17:32:50Z | - |
dc.date.available | 2015-04-24T17:32:50Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0168-3659 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105606 | - |
dc.description.abstract | Ischemic heart disease is a rapidly increasing common cause of death in the world. This disease is the insufficient status of oxygen within the cardiac muscles due to an imbalance between oxygen supply and demand, and a cardiac disease that occurs as a result of coronary artery stenosis. Conventional surgery-based therapy for the treatment of ischemic heart diseases has been advanced with biopharmaceutical-based therapy, such as protein, gene and cell therapy. The conventional medical therapy focuses on the use of drug eluting stents, coronary-artery bypass-graft surgery and anti-thrombosis. Biopharmaceutical-based therapies including recombinant protein therapy, gene therapy and cell transplantation are recognized as promising approaches in inducing neovascularization and improving collateral blood flow in the ischemic heart. This review explores the current status and future of the treatment of ischemic heart diseases with conventional medical therapy, biopharmaceutical-based therapy focused on the proteins and polymeric hydrogels for delivery of therapeutic proteins. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 194~202 | - |
dc.relation.isPartOf | JOURNAL OF CONTROLLED RELEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cell- and Tissue-Based Therapy | - |
dc.subject.MESH | Coronary Artery Bypass | - |
dc.subject.MESH | Drug Delivery Systems | - |
dc.subject.MESH | Excipients | - |
dc.subject.MESH | Fibrinolytic Agents/therapeutic use | - |
dc.subject.MESH | Genetic Therapy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hydrogels | - |
dc.subject.MESH | Myocardial Ischemia/drug therapy | - |
dc.subject.MESH | Myocardial Ischemia/surgery | - |
dc.subject.MESH | Myocardial Ischemia/therapy* | - |
dc.subject.MESH | Proteins/administration & dosage | - |
dc.subject.MESH | Proteins/therapeutic use | - |
dc.title | Ischemic heart diseases: current treatments and future | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Life Science (의생명과학부) | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Ki-Chul Hwang | - |
dc.contributor.googleauthor | Kuen-Yong Lee | - |
dc.contributor.googleauthor | Yong-Hee Kim | - |
dc.identifier.doi | 10.1016/j.jconrel.2009.06.016 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A04456 | - |
dc.relation.journalcode | J01352 | - |
dc.identifier.eissn | 1873-4995 | - |
dc.identifier.pmid | 19563848 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0168365909004362 | - |
dc.subject.keyword | Ischemic heart disease | - |
dc.subject.keyword | Percutaneous coronary intervention | - |
dc.subject.keyword | Protein therapy | - |
dc.subject.keyword | Cell and gene therapy | - |
dc.subject.keyword | Polymeric drug delivery system | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.alternativeName | Hwang, Ki Chul | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Hwang, Ki Chul | - |
dc.citation.volume | 140 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 194 | - |
dc.citation.endPage | 202 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CONTROLLED RELEASE, Vol.140(3) : 194-202, 2009 | - |
dc.identifier.rimsid | 40914 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.