Cited 0 times in
1형 당뇨병 환자에서 생리주기 이상
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김덕희 | - |
dc.contributor.author | 김호성 | - |
dc.contributor.author | 채현욱 | - |
dc.date.accessioned | 2015-04-24T17:32:35Z | - |
dc.date.available | 2015-04-24T17:32:35Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1226-2242 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105598 | - |
dc.description.abstract | Purpose: This study compares the prevalence of pubertal menstrual disorders in type 1 diabetes mellitus (DM) patients with that in normal subjects. Methods: A questionnaire was used to obtain data on pubertal development and menstrual history from 43 type 1 DM patients, who were diagnosed at the pediatrics department of Severance Children’s Hospital, Yonsei University, and 56 normal control subjects. We evaluated the estrogen levels in all type 1 DM patients. Results: The age at onset of puberty did not significantly differ between the 2 groups. However, the prevalence of oligomenorrhea in type 1 DM patients (21.21%) was significantly higher than that in the control group (2.08%; P?0.05). In addition, the incidence of amenorrhea in type 1 DM patients (20.59%) was significantly higher than that in the control group (2.08%; P?0.05 ). Pubertal development in type 1 DM patients was delayed due to elevated levels of glycosylated hemoglobin (HbA1c). The delay (9 months) in pubertal development in the patients diagnosed with type 1 DM at prepubertal ages was shorter than that (14.8 months) in the patients diagnosed with type 1 DM at postpubertal age (P?0.05). The level of LH, FSH were higher and E2 level was lower in DM patients compared to control group, especially in diabetics with amenorrhea (P?0.05). Conclusion: We observed a high frequency of delayed pubertal development and menstruation irregularities in patients who were diagnosed with type 1 DM at the prepubertal age or in type 1 DM patients with high levels of HbA1c. This finding can be attributed to the decreased plasma levels of E2 or due to the decreased E2 activity in patients with type 1 DM. Further evaluation of hormonal changes in type 1 DM patients is essential | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 116~123 | - |
dc.relation.isPartOf | Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 1형 당뇨병 환자에서 생리주기 이상 | - |
dc.title.alternative | Menstrual Disorders in Patients with Type I Diabetes Mellitus | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | 권아름 | - |
dc.contributor.googleauthor | 채현욱 | - |
dc.contributor.googleauthor | 김호성 | - |
dc.contributor.googleauthor | 김덕희 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00378 | - |
dc.contributor.localId | A01184 | - |
dc.contributor.localId | A04026 | - |
dc.relation.journalcode | J01548 | - |
dc.subject.keyword | Menstruation disorders | - |
dc.subject.keyword | Diabetes mellitus | - |
dc.subject.keyword | Type 1 | - |
dc.subject.keyword | Puberty | - |
dc.subject.keyword | Amenorrhea | - |
dc.contributor.alternativeName | Kim, Duk Hee | - |
dc.contributor.alternativeName | Kim, Ho Seong | - |
dc.contributor.alternativeName | Chae, Hyun Wook | - |
dc.contributor.affiliatedAuthor | Kim, Duk Hee | - |
dc.contributor.affiliatedAuthor | Kim, Ho Seong | - |
dc.contributor.affiliatedAuthor | Chae, Hyun Wook | - |
dc.citation.volume | 14 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 116 | - |
dc.citation.endPage | 123 | - |
dc.identifier.bibliographicCitation | Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지), Vol.14(2) : 116-123, 2009 | - |
dc.identifier.rimsid | 40908 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.