Cited 7 times in
A Case of Immune Hemolytic Anemia Induced by Ceftizoxime and Cefobactam (Sulbactam/Cefoperazone).
DC Field | Value | Language |
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dc.contributor.author | 김신영 | - |
dc.contributor.author | 김현옥 | - |
dc.contributor.author | 백은정 | - |
dc.date.accessioned | 2015-04-24T17:31:39Z | - |
dc.date.available | 2015-04-24T17:31:39Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1598-6535 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105568 | - |
dc.description.abstract | Simultaneous drug-induced immune hemolytic anemia (DIIHA) caused by multiple drugs is rare. We report a case of a patient who developed DIIHA caused by 2 drugs. The patient's serum exhibited agglutination of ceftizoxime- or sulbactam-coated red blood cells (RBCs; via a drug-adsorption mechanism) and of uncoated RBCs in the presence of sulbactam (via an immune-complex mechanism). Although ceftizoxime is known to exhibit a positive reaction by an immune-complex method with or without reactivity with drug-coated RBCs, this patient's antibodies were reactive only against drug-coated RBCs. On the other hand, sulbactam, which is known to cause hemolytic anemia by nonimmunologic protein adsorption, exhibited positive reactions in tests with both drug-coated RBCs and in the presence of sulbactam. This is the first report of DIIHA due to a sulbactam-cefoperazone combination and the fourth report of DIIHA due to ceftizoxime. Owing to the patient's complicated laboratory results, DIIHA was suspected only at a late stage. We propose that for the prompt diagnosis of DIIHA, tests for all possible causative drugs should be conducted by 2 methods. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 578~584 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF LABORATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anemia,Hemolytic/chemicallyinduced | - |
dc.subject.MESH | Anemia,Hemolytic/diagnosis* | - |
dc.subject.MESH | Anemia,Hemolytic/immunology | - |
dc.subject.MESH | Anti-Bacterial Agents/adverse effects* | - |
dc.subject.MESH | Cefoperazone/adverse effects* | - |
dc.subject.MESH | Ceftizoxime/adverse effects* | - |
dc.subject.MESH | Erythrocytes/chemistry | - |
dc.subject.MESH | Erythrocytes/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Sulbactam/adverse effects* | - |
dc.title | A Case of Immune Hemolytic Anemia Induced by Ceftizoxime and Cefobactam (Sulbactam/Cefoperazone). | - |
dc.title.alternative | Ceftizoxime과 Cefobactam에 의한 면역용혈성 빈혈 1예 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Eun Jung Baek | - |
dc.contributor.googleauthor | Sungsil Lee | - |
dc.contributor.googleauthor | Sinyoung Kim | - |
dc.contributor.googleauthor | Hyun Kyung Choi | - |
dc.contributor.googleauthor | Hyun Ok Kim | - |
dc.identifier.doi | 10.3343/kjlm.2009.29.6.578 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00675 | - |
dc.contributor.localId | A01122 | - |
dc.contributor.localId | A01830 | - |
dc.relation.journalcode | J02044 | - |
dc.identifier.pmid | 20046091 | - |
dc.subject.keyword | Drug-induced immune hemolytic anemia | - |
dc.subject.keyword | Beta-lactamase inhibitor antibody | - |
dc.subject.keyword | Cephalosporin antibody | - |
dc.subject.keyword | Ceftizoxime antibody | - |
dc.contributor.alternativeName | Kim, Sin Young | - |
dc.contributor.alternativeName | Kim, Hyun Ok | - |
dc.contributor.alternativeName | Baek, Eun Jung | - |
dc.contributor.affiliatedAuthor | Kim, Sin Young | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Ok | - |
dc.contributor.affiliatedAuthor | Baek, Eun Jung | - |
dc.citation.volume | 29 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 578 | - |
dc.citation.endPage | 584 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF LABORATORY MEDICINE , Vol.29(6) : 578-584, 2009 | - |
dc.identifier.rimsid | 44355 | - |
dc.type.rims | ART | - |
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