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Evaluation in 3 months duration of neointimal coverage after zotarolimus-eluting stent implantation by optical coherence tomography: the ENDEAVOR OCT trial.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최의영 | - |
dc.contributor.author | 홍명기 | - |
dc.contributor.author | 고영국 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 김진선 | - |
dc.contributor.author | 김태훈 | - |
dc.contributor.author | 박상민 | - |
dc.contributor.author | 이상학 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 최동훈 | - |
dc.date.accessioned | 2015-04-24T17:30:21Z | - |
dc.date.available | 2015-04-24T17:30:21Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1936-8798 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105526 | - |
dc.description.abstract | OBJECTIVES: We performed this study to investigate the vascular response in early period after zotarolimus-eluting stent (ZES) (Endeavor Sprint, Medtronic CardioVascular, Minneapolis, Minnesota) implantation. BACKGROUND: The ZES has different characteristics, with biocompatible polymer and rapid drug-elution, compared with the first-generation drug-eluting stents (DES). METHODS: The ENDEAVOR OCT (Evaluation in 3 Months Duration of Neointimal Coverage after Zotarolimus-Eluting Stent Implantation by Optical Coherence Tomography) trial is a prospective, single-center study evaluating vascular healing patterns with optical coherence tomography (OCT) at 3 months after stent implantation. A total of 31 ZES in 30 patients underwent serial OCT at immediate post-intervention and 3 months. Neointimal growth and malapposition were analyzed at each stent strut of cross-sectional OCT images with 0.5-mm intervals. RESULTS: The incidence of malapposition at post-intervention and 3 months was 6.0% and 0.2%, respectively. However, late acquired malapposition was not detected at 3 months. Of 31 stents, 27 stents (87.1%) were covered completely with neointima, but the remaining 4 stents had 2 (0.8%), 4 (0.9%), 4 (1.2%), and 6 (1.4%) uncovered struts. Overall mean percentage of covered stent struts was 99.9 +/- 0.4%. This finding was consistent among groups with acute coronary syndrome and stable angina pectoris (99.9 +/- 0.3% vs. 99.9 +/- 0.4%, p = 0.92). Intracoronary thrombus was documented in 1 stent (3.2%) among 31 stents. CONCLUSIONS: Most of the stent struts were covered with neointima, and late acquired malapposition was not found at 3 months after ZES implantation. Therefore, the current study demonstrated that ZES might have a favorable in vivo vascular response at 3 months after stent implantation. (Evaluation of Zotarolimus Eluting Stent at 3 Months Using Optical Coherence Tomography [ENDEAVOR OCT]; NCT00815139). | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1240~1247 | - |
dc.relation.isPartOf | JACC-CARDIOVASCULAR INTERVENTIONS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary/adverse effects | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary/instrumentation* | - |
dc.subject.MESH | Cardiovascular Agents/administration & dosage* | - |
dc.subject.MESH | Coronary Angiography | - |
dc.subject.MESH | Coronary Artery Disease/pathology | - |
dc.subject.MESH | Coronary Artery Disease/therapy* | - |
dc.subject.MESH | Coronary Vessels/pathology* | - |
dc.subject.MESH | Drug-Eluting Stents* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Prosthesis Design | - |
dc.subject.MESH | Sirolimus/administration & dosage | - |
dc.subject.MESH | Sirolimus/analogs & derivatives* | - |
dc.subject.MESH | Thrombosis/etiology | - |
dc.subject.MESH | Thrombosis/pathology | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Tomography, Optical Coherence* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Tunica Intima/pathology* | - |
dc.subject.MESH | Ultrasonography, Interventional | - |
dc.title | Evaluation in 3 months duration of neointimal coverage after zotarolimus-eluting stent implantation by optical coherence tomography: the ENDEAVOR OCT trial. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Ik-Kyung Jang | - |
dc.contributor.googleauthor | Chunyu Fan | - |
dc.contributor.googleauthor | Tae Hoon Kim | - |
dc.contributor.googleauthor | Jin-Sun Kim | - |
dc.contributor.googleauthor | Sang Min Park | - |
dc.contributor.googleauthor | Eui-Young Choi | - |
dc.contributor.googleauthor | Sang Hak Lee | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Myeong-Ki Hong | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.identifier.doi | 10.1016/j.jcin.2009.10.006 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04165 | - |
dc.contributor.localId | A04391 | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A00961 | - |
dc.contributor.localId | A01485 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A02833 | - |
dc.contributor.localId | A01018 | - |
dc.contributor.localId | A01085 | - |
dc.relation.journalcode | J01193 | - |
dc.identifier.eissn | 1876-7605 | - |
dc.identifier.pmid | 20129551 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1936879809007213 | - |
dc.subject.keyword | drug-eluting stent | - |
dc.subject.keyword | optical coherence | - |
dc.subject.keyword | tomography | - |
dc.subject.keyword | zotarolimus | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.contributor.alternativeName | Hong, Myeong Ki | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Kim, Jung Sun | - |
dc.contributor.alternativeName | Kim, Jin Sun | - |
dc.contributor.alternativeName | Kim, Tae Hoon | - |
dc.contributor.alternativeName | Park, Sang Min | - |
dc.contributor.alternativeName | Lee, Sang Hak | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Eui Young | - |
dc.contributor.affiliatedAuthor | Hong, Myeong Ki | - |
dc.contributor.affiliatedAuthor | Ko, Young Guk | - |
dc.contributor.affiliatedAuthor | Kim, Jung Sun | - |
dc.contributor.affiliatedAuthor | Park, Sang Min | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Snag Hak | - |
dc.contributor.affiliatedAuthor | Kim, Jin Sun | - |
dc.contributor.affiliatedAuthor | Kim, Tae-Hoon | - |
dc.citation.volume | 2 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1240 | - |
dc.citation.endPage | 1247 | - |
dc.identifier.bibliographicCitation | JACC-CARDIOVASCULAR INTERVENTIONS, Vol.2(12) : 1240-1247, 2009 | - |
dc.identifier.rimsid | 44331 | - |
dc.type.rims | ART | - |
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