국내 한 대학병원 혈액원에서의 헌혈자 선별검사 결과(2006∼2008)

Abstract

Background: Any data on the prevalence of the infectious diseases of blood donors at a university hospital-based blood bank is not available. We aimed to analyze the seroincidence of screening tests from blood donors at a university hospital-based blood bank in Korea. Methods: We retrospectively analyzed all the samples of blood donors during the previous three years from January 2006 to December 2008. HBsAg and HIV Ab/Ag Combo test were performed by chemiluminescent immunoassays, and anti-HCV was performed by enzyme-linked immunosorbent assay and electrochemiluminescent immunoassay. Serologic testing for syphilis was done by VDRL (venereal disease research laboratory test) and RPR (rapid plasma regain test). Results: The number of total blood donors that underwent screening tests were 1,279 in 2006, 1,355 in 2007 and 941 in 2008, respectively. HBsAg was positive in 8 cases among the 1,279 donors (0.63%) in 2006, in 10 cases of the 1,355 donors (0.74%) in 2007 and in 5 cases of the 941 donors (0.53%) in 2008. Anti-HCV was positive in 3 cases (0.24%) in 2006, 2 cases (0.15%) in 2007 and 2 cases (0.21%) in 2008. One of them was dual positive for HBsAg and anti-HCV. There's no positive case of anti-HIV (0%) during the 3 years. Serologic testing for syphilis (VDRL) was positive in 7 cases (0.55%) in 2006, in 5 cases (0.37%) in 2007 and in 5 cases (0.53%) in 2008. Conclusion: The seroincidence was different between a university hospital-based blood bank and the Korean Red Cross Blood Service center. This difference might be due to the composition of donors, i.e., autologous blood donors and directed donors in the university-based blood bank