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Muscle weakness after repeated injection of botulinum toxin type A evaluated according to bite force measurement of human masseter muscle
DC Field | Value | Language |
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dc.contributor.author | 김기서 | - |
dc.contributor.author | 김성택 | - |
dc.date.accessioned | 2015-04-24T17:28:18Z | - |
dc.date.available | 2015-04-24T17:28:18Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1076-0512 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105461 | - |
dc.description.abstract | BACKGROUND: Botulinum toxin type A (BTX-A) has been applied successfully to treat masseteric hypertrophy, but it can cause muscle weakness. OBJECTIVE: To measure the change in maximum bite force (MBF) after BTX-A injection into the human masseter muscle and to evaluate the influence of a booster (repeated) injection. METHODS: Thirty volunteers completed 18-week follow-up, and MBF was measured. At 18 weeks after the first injection, a booster injection was given to 14 patients, and they were followed up until 18 weeks from the booster injection. RESULTS: Mean MBF was approximately 20% lower at 2 weeks than before the injection, and it recovered gradually after 4 weeks to return to the preinjection level at 12 weeks. MBF differed significantly between before the injection and at 2, 4, and 8 weeks after the injection (p<.05). In the booster injection group (n=14), MBF was markedly lower at 6 weeks (p<.05), and it recovered gradually in 12 weeks. CONCLUSION: MBF was significantly lower after booster injection of BTX-A into the human masseter muscle, but it gradually recovered in a predictable pattern, and the degree of discomfort experienced by the subjects had little effect on normal mastication | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1902~1907 | - |
dc.relation.isPartOf | DERMATOLOGIC SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Bite Force* | - |
dc.subject.MESH | Botulinum Toxins, Type A/administration & dosage | - |
dc.subject.MESH | Botulinum Toxins, Type A/pharmacology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertrophy/drug therapy | - |
dc.subject.MESH | Injections, Intramuscular | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Masseter Muscle/drug effects* | - |
dc.subject.MESH | Masseter Muscle/pathology | - |
dc.subject.MESH | Muscle Weakness/chemically induced* | - |
dc.subject.MESH | Neuromuscular Agents/administration & dosage | - |
dc.subject.MESH | Neuromuscular Agents/pharmacology* | - |
dc.title | Muscle weakness after repeated injection of botulinum toxin type A evaluated according to bite force measurement of human masseter muscle | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Medicine (구강내과학) | - |
dc.contributor.googleauthor | KI SEO KIM | - |
dc.contributor.googleauthor | YOUNG SUB BYUN | - |
dc.contributor.googleauthor | YONG JEONG KIM | - |
dc.contributor.googleauthor | SEONG TAEK KIM | - |
dc.identifier.doi | 10.1111/j.1524-4725.2009.01319.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00335 | - |
dc.contributor.localId | A00588 | - |
dc.relation.journalcode | J00707 | - |
dc.identifier.eissn | 1524-4725 | - |
dc.identifier.pmid | 19737290 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1524-4725.2009.01319.x/abstract | - |
dc.contributor.alternativeName | Kim, Ki Seo | - |
dc.contributor.alternativeName | Kim, Seong Taek | - |
dc.contributor.affiliatedAuthor | Kim, Ki Seo | - |
dc.contributor.affiliatedAuthor | Kim, Seong Taek | - |
dc.citation.volume | 35 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1902 | - |
dc.citation.endPage | 1907 | - |
dc.identifier.bibliographicCitation | DERMATOLOGIC SURGERY, Vol.35(12) : 1902-1907, 2009 | - |
dc.identifier.rimsid | 44279 | - |
dc.type.rims | ART | - |
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