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Ciprofloxacin에 불량한 치료반응을 보인 인도 유입형 파라티푸스 2예

Other Titles
 Two cases of imported paratyphoid fever with poor response to ciprofloxacin following travel to India 
 김송이  ;  이남석  ;  노진규  ;  권용환  ;  한상훈  ;  어 영  ;  김효열 
 Korean Journal of Medicine, Vol.77(Suppl 2) : 469-473, 2009 
Journal Title
Korean Journal of Medicine
Issue Date
Cephalosporins ; Ciprofloxacin ; Paratyphoid fever
It is well known that paratyphoid fever is caused by Salmonella enterica serotype paratyphi (S. paratyphi) and usually responds
to ciprofloxacin treatment. Recently, many reports have recommended that S. paratyphi with nalidixic acid resistance should be
considered if paratyphoid fever does not improved with ciprofloxacin treatment. We experienced two patients who were diagnosed
with paratyphoid fever after traveling to India. the paratyphoid fever was caused by ciprofloxacin-susceptible and intermediate S.
paratyphi infection; however, the patients became refractory to treatment with ciprofloxacin. After 7 days of treatment with ciprofloxacin,
we changed the antibiotic treatment to a third-generation cephalosporin. Sustained fever and watery diarrhea was improved
within 3 days after changing the antibiotics. in uncomplicated cases of paratyphoid fever, an adequate dose of ciprofloxacin
can be given initially. If clinical improvement is not noted after 3 to 5 days, however, third-generation cephalosporins should be
considered as an alternative regimen.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Song Yee(김송이) ORCID logo https://orcid.org/0000-0001-8627-486X
Han, Sang Hoon(한상훈) ORCID logo https://orcid.org/0000-0002-4278-5198
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