Case Report of Pediatric Gastroenteritis Due to CTX-M-15 Extended-Spectrum beta-Lactamase-Producing Salmonella enterica Serotype Enteritidis.

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Other Titles: CTX-M-15 Extended-Spectrum β-Lactamase 생성 Salmonella enterica Serotype Enteritidis에 의한 소아 위장염 증례보고

Authors: Kon Hee Lee ; Wonkeun Song ; Seok Hoon Jeong ; Ka Young Choi ; Hae Sun Yoon ; Min-Jeong Park

MeSH: Child, Preschool ; Gastroenteritis/diagnosis ; Gastroenteritis/microbiology* ; Humans ; Male ; Salmonella enteritidis/genetics ; Salmonella enteritidis/isolation & purification* ; Serotyping ; beta-Lactamases/genetics*

Abstract: A clinical isolate of Salmonella enterica serotype Enteritidis in Korea was found to produce the extended-spectrum beta-lactamase CTX-M-15. The isolate was recovered in 2008 from the stool of a 3-yr-old boy with gastroenteritis. This isolate was found to be resistant to multiple drugs, including ampicillin, piperacillin, cefotaxime, ceftazidime, cefepime, and aztreonam. The resistance to cefotaxime was transferred by conjugation to recipient Escherichia coli J53. The patient was eventually successfully treated with trimethoprim-sulfamethoxazole. This is the first report of the bla (CTX-M-15) gene in S. enterica serotype Enteritidis in Korea.