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Body mass index and stroke mortality by smoking and age at menopause among Korean postmenopausal women

DC Field Value Language
dc.contributor.author남정모-
dc.contributor.author설재웅-
dc.contributor.author오희철-
dc.date.accessioned2015-04-24T17:21:23Z-
dc.date.available2015-04-24T17:21:23Z-
dc.date.issued2009-
dc.identifier.issn0039-2499-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/105245-
dc.description.abstractBACKGROUND AND PURPOSE: The association between body mass index and mortality caused by subtypes of stroke among postmenopausal women in terms of smoking status and age at menopause remains controversial. METHODS: The data were derived from a cohort study of 3321 with 17.8 years of follow-up (1985 to 2002). Hazard ratios (HRs) and 95% CIs for strokes as related to body mass index were estimated by Cox proportional hazard models adjusted for age, hypertension, smoking, drinking, occupation, education, self-reported health, and age at menopause. A stratified analysis was conducted by age at menopause and smoking status. RESULTS: The obese group (body mass index >or=27.5 kg/m(2)) had higher risks of total stroke mortality (HR, 1.59; 95% CI, 1.05 to 2.42) and hemorrhagic stroke mortality (HR, 2.91; 95% CI, 1.37 to 6.19) than the normal weight group (18.5<or= body mass index <23.0). Among ever smokers, the obese group showed significantly increased risks of total stroke mortality (HR, 2.33; 95% CI, 1.00 to 5.43) and ischemic stroke mortality (HR, 7.21; 95% CI, 1.18 to 44.3). Obesity had more effect on stroke mortality among women who experienced menopause at age <50 than women with age >or=50. For the obese group of the former, the HR of total stroke was 2.04 (95% CI, 1.25 to 3.34) and that of hemorrhagic stroke 6.46 (95% CI, 2.42 to 17.25). CONCLUSIONS: In this prospective study, obesity raised the risks of total stroke mortality and hemorrhagic stroke mortality among Korean menopausal women. It was more evident with women who experienced menopause at age <50. The obese group of ever smokers was at an increased risk of ischemic stroke mortality.-
dc.description.statementOfResponsibilityopen-
dc.format.extent3428~3435-
dc.relation.isPartOfSTROKE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAge Factors-
dc.subject.MESHAged-
dc.subject.MESHAsian Continental Ancestry Group*-
dc.subject.MESHBody Mass Index*-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHKorea-
dc.subject.MESHMenopause*/physiology-
dc.subject.MESHMiddle Aged-
dc.subject.MESHObesity/complications-
dc.subject.MESHObesity/mortality-
dc.subject.MESHPostmenopause*/physiology-
dc.subject.MESHProspective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHSmoking/adverse effects-
dc.subject.MESHSmoking/mortality*-
dc.subject.MESHSmoking/physiopathology-
dc.subject.MESHStroke/mortality*-
dc.subject.MESHStroke/physiopathology-
dc.titleBody mass index and stroke mortality by smoking and age at menopause among Korean postmenopausal women-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Preventive Medicine (예방의학)-
dc.contributor.googleauthorSang-Wook Yi-
dc.contributor.googleauthorNemekhee Odongua-
dc.contributor.googleauthorChung Mo Nam-
dc.contributor.googleauthorJae Woong Sull-
dc.contributor.googleauthorHeechoul Ohrr-
dc.identifier.doi10.1161/STROKEAHA.109.555144-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01264-
dc.contributor.localIdA01942-
dc.contributor.localIdA02419-
dc.relation.journalcodeJ02690-
dc.identifier.eissn1524-4628-
dc.identifier.pmid19696422-
dc.subject.keywordAsian-
dc.subject.keywordcohort study-
dc.subject.keywordbody mass index-
dc.subject.keywordKorean-
dc.subject.keywordmenopause-
dc.subject.keywordmortality-
dc.subject.keywordsmoking-
dc.subject.keywordstroke-
dc.contributor.alternativeNameNam, Jung Mo-
dc.contributor.alternativeNameSull, Jae Woong-
dc.contributor.alternativeNameOhrr, Hee Choul-
dc.contributor.affiliatedAuthorNam, Jung Mo-
dc.contributor.affiliatedAuthorSull, Jae Woong-
dc.contributor.affiliatedAuthorOhrr, Hee Choul-
dc.citation.volume40-
dc.citation.number11-
dc.citation.startPage3428-
dc.citation.endPage3435-
dc.identifier.bibliographicCitationSTROKE, Vol.40(11) : 3428-3435, 2009-
dc.identifier.rimsid54243-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers

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