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혈소판 수혈 단위수의 제한으로 인한 수혈효과와 유용성

DC FieldValueLanguage
dc.contributor.author김현옥-
dc.contributor.author이양순-
dc.date.accessioned2015-04-24T17:21:04Z-
dc.date.available2015-04-24T17:21:04Z-
dc.date.issued2009-
dc.identifier.issn1598-6535-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/105235-
dc.description.abstractBACKGROUND: In Korea, a platelet transfusion dose (TD) of 8 units of platelet concentrates (PC) is usually used. To minimize the shortage of blood products and transfusion-related adverse reactions, the TD has been changed from 8 to 6 units in 2006 in our hospital. Here, we analyzed the dose reduction effect on patients' platelet counts and transfusion frequency. METHODS: We compared the amount of issued PC, platelet counts before and after transfusion, post-transfusion platelet increments, and transfusion frequencies in patients who were transfused with 8 PC in 2006 and 6 PC in 2008. RESULTS: Despite an increase in the number of admitted patients by 20% in 2008 with a disease distribution similar to that in 2006, the number of issued PC in 2008 was decreased by 26.6% compared to that in 2006. In 2008, post-transfusion platelet counts, pre-transfusion platelet counts in patients transfused with 320 mL whole blood-derived PC, and platelet increments in patients transfused with 400 mL whole blood-derived PC were significantly decreased. However, the mean transfusion frequency per one month was not significantly different, 4.3 times in 2006 and 4.7 in 2008. CONCLUSIONS: By implementing a policy of platelet TD restriction, the amount of total issued PC was markedly decreased. Although post-transfusion platelet counts were decreased, the transfusion frequency in a month was not significantly increased. The restriction of platelet TD was helpful for increasing physicians' recognition of blood shortage while achieving similar transfusion effects. We conclude that 6 units of PC would be a better guideline for the platelet TD-
dc.description.statementOfResponsibilityopen-
dc.format.extent158~162-
dc.relation.isPartOfKOREAN JOURNAL OF LABORATORY MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHEvaluation Studies as Topic-
dc.subject.MESHHumans-
dc.subject.MESHOrganizational Policy-
dc.subject.MESHPlatelet Count-
dc.subject.MESHPlatelet Transfusion*-
dc.title혈소판 수혈 단위수의 제한으로 인한 수혈효과와 유용성-
dc.title.alternativeReduction of the Platelet Transfusion Dose and Its Effects-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthor백은정-
dc.contributor.googleauthor이양순-
dc.contributor.googleauthor김효식-
dc.contributor.googleauthor배인철-
dc.contributor.googleauthor김현옥-
dc.identifier.doi10.3343/kjlm.2009.29.2.158-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01122-
dc.contributor.localIdA02947-
dc.relation.journalcodeJ02044-
dc.identifier.pmid19411784-
dc.subject.keywordPlatelet-
dc.subject.keywordTransfusion dose-
dc.subject.keywordAdequate transfusion-
dc.subject.keywordTransfusion guidelines-
dc.contributor.alternativeNameKim, Hyun Ok-
dc.contributor.alternativeNameLee, Yang Soon-
dc.contributor.affiliatedAuthorKim, Hyun Ok-
dc.contributor.affiliatedAuthorLee, Yang Soon-
dc.citation.volume29-
dc.citation.number2-
dc.citation.startPage158-
dc.citation.endPage162-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF LABORATORY MEDICINE , Vol.29(2) : 158-162, 2009-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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