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혈소판 수혈 단위수의 제한으로 인한 수혈효과와 유용성

Other Titles
 Reduction of the Platelet Transfusion Dose and Its Effects 
Authors
 백은정  ;  이양순  ;  김효식  ;  배인철  ;  김현옥 
Citation
 KOREAN JOURNAL OF LABORATORY MEDICINE , Vol.29(2) : 158-162, 2009 
Journal Title
 KOREAN JOURNAL OF LABORATORY MEDICINE 
ISSN
 1598-6535 
Issue Date
2009
MeSH
Evaluation Studies as Topic ; Humans ; Organizational Policy ; Platelet Count ; Platelet Transfusion*
Keywords
Platelet ; Transfusion dose ; Adequate transfusion ; Transfusion guidelines
Abstract
BACKGROUND: In Korea, a platelet transfusion dose (TD) of 8 units of platelet concentrates (PC) is usually used. To minimize the shortage of blood products and transfusion-related adverse reactions, the TD has been changed from 8 to 6 units in 2006 in our hospital. Here, we analyzed the dose reduction effect on patients' platelet counts and transfusion frequency. METHODS: We compared the amount of issued PC, platelet counts before and after transfusion, post-transfusion platelet increments, and transfusion frequencies in patients who were transfused with 8 PC in 2006 and 6 PC in 2008. RESULTS: Despite an increase in the number of admitted patients by 20% in 2008 with a disease distribution similar to that in 2006, the number of issued PC in 2008 was decreased by 26.6% compared to that in 2006. In 2008, post-transfusion platelet counts, pre-transfusion platelet counts in patients transfused with 320 mL whole blood-derived PC, and platelet increments in patients transfused with 400 mL whole blood-derived PC were significantly decreased. However, the mean transfusion frequency per one month was not significantly different, 4.3 times in 2006 and 4.7 in 2008. CONCLUSIONS: By implementing a policy of platelet TD restriction, the amount of total issued PC was markedly decreased. Although post-transfusion platelet counts were decreased, the transfusion frequency in a month was not significantly increased. The restriction of platelet TD was helpful for increasing physicians' recognition of blood shortage while achieving similar transfusion effects. We conclude that 6 units of PC would be a better guideline for the platelet TD
Files in This Item:
T200903632.pdf Download
DOI
10.3343/kjlm.2009.29.2.158
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyun Ok(김현옥) ORCID logo https://orcid.org/0000-0002-4964-1963
Lee, Yang Soon(이양순)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105235
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