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Stimulatory effects of ferulic acid on endurance exercise capacity in mice

DC FieldValueLanguage
dc.contributor.author윤호근-
dc.date.accessioned2015-04-24T17:12:37Z-
dc.date.available2015-04-24T17:12:37Z-
dc.date.issued2009-
dc.identifier.issn0916-8451-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104962-
dc.description.abstractFerulic acid was orally administered to mice in order to investigate its effects on exercise endurance capacity. When a single administration of ferulic acid was given to the mice in an adjustable-current water pool, the duration of exhaustive swimming was longer than that exhibited by the mice in the control group. Also, when the mice were exhaustively exercised for 3 consecutive days, no change in swimming time was found in the ferulic acid-administered group on the final day, and a large decrease in the untreated mice. Administration of ferulic acid efficiently activated the hepatic antioxidative defense system during exercise. The mice that received ferulic acid showed significant increases in the activity of hepatic antioxidant enzymes such as superoxide dismutase, catalase, and glutathione-S-transferase. Furthermore, an increased glutathione level was observed, while the malondialdehyde content was reduced. These results suggest that ferulic acid possesses stimulatory effects that can enhance exercise endurance capacity and reduce fatigue by elevating antioxidative potentials.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1392~1397-
dc.relation.isPartOfBIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHAntioxidants/metabolism-
dc.subject.MESHCoumaric Acids/pharmacology*-
dc.subject.MESHFatigue/prevention & control-
dc.subject.MESHGlutathione/metabolism-
dc.subject.MESHLiver/metabolism-
dc.subject.MESHMalondialdehyde/metabolism-
dc.subject.MESHMice-
dc.subject.MESHPhysical Conditioning, Animal*-
dc.subject.MESHPhysical Endurance*-
dc.titleStimulatory effects of ferulic acid on endurance exercise capacity in mice-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Biochemistry & Molecular Biology (생화학,분자생물학)-
dc.contributor.googleauthorYanghee YOU-
dc.contributor.googleauthorJeongjin PARK Ho-Geun YOON-
dc.contributor.googleauthorYoo-Hyun LEE-
dc.contributor.googleauthorKwontack HWANG-
dc.contributor.googleauthorJeongmin LEE-
dc.contributor.googleauthorKyungmi KIM-
dc.contributor.googleauthorKwang-Won LEE-
dc.contributor.googleauthorSangin SHIM-
dc.contributor.googleauthorWoojin JUN-
dc.identifier.doi10.1271/bbb.90062-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02625-
dc.relation.journalcodeJ00328-
dc.identifier.eissn1347-6947-
dc.identifier.pmid19502723-
dc.subject.keywordferulic acid-
dc.subject.keywordexercise endurance capacity-
dc.subject.keywordfatigue-
dc.subject.keywordantioxidation-
dc.contributor.alternativeNameYoon, Ho Geun-
dc.contributor.affiliatedAuthorYoon, Ho Geun-
dc.citation.volume73-
dc.citation.number6-
dc.citation.startPage1392-
dc.citation.endPage1397-
dc.identifier.bibliographicCitationBIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Vol.73(6) : 1392-1397, 2009-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biochemistry and Molecular Biology (생화학-분자생물학교실) > 1. Journal Papers

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