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Risk factors of survival and surgical treatment for advanced gastric cancer with large tumor size

DC FieldValueLanguage
dc.contributor.author김성수-
dc.contributor.author노성훈-
dc.contributor.author오성진-
dc.contributor.author형우진-
dc.date.accessioned2015-04-24T17:10:41Z-
dc.date.available2015-04-24T17:10:41Z-
dc.date.issued2009-
dc.identifier.issn1091-255X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104903-
dc.description.abstractBACKGROUND: The purpose of this study was to clarify the clinical significance of tumor size in advanced gastric cancer and to evaluate the risk factors of survival in advanced gastric cancer with large tumor size. METHODS: The cut-off point for tumor size, 90th percentile value of tumor size in advanced gastric cancer, was determined to be 10 cm. We retrospectively studied the clinicopathological features and prognosis of 406 patients with advanced gastric tumors measuring 10 cm or more. RESULTS: Large tumors had a propensity for the following: Borrmann type IV, adjacent organ invasion, lymph node and distant metastasis, and stage IV classification. Tumor size was an independent risk factor for lymph node metastasis and survival in advanced gastric cancer. In patients with large advanced gastric cancer, Borrmann type IV, adjacent organ invasion, and N2-3 nodal involvement were independent factors associated with a poorer prognosis. The 5-year survival rate in large gastric cancer patients without any risk factors (65.5%) was similar with those in small gastric cancer patients (59.3%, P = 0.123). CONCLUSION: Tumor size was a simple predictor for lymph node metastasis and survival in advanced gastric cancer. Radical surgery should be recommended for large advanced gastric cancer patients without risk factors, while large gastric cancer with risk factors may not be a surgically treatable disease.-
dc.description.statementOfResponsibilityopen-
dc.format.extent881~885-
dc.relation.isPartOfJOURNAL OF GASTROINTESTINAL SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHGastrectomy-
dc.subject.MESHHumans-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Invasiveness-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHStomach Neoplasms/mortality*-
dc.subject.MESHStomach Neoplasms/pathology*-
dc.subject.MESHStomach Neoplasms/surgery-
dc.subject.MESHSurvival Rate-
dc.subject.MESHTumor Burden-
dc.titleRisk factors of survival and surgical treatment for advanced gastric cancer with large tumor size-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorChen Li-
dc.contributor.googleauthorSung Jin Oh-
dc.contributor.googleauthorSungsoo Kim-
dc.contributor.googleauthorWoo Jin Hyung-
dc.contributor.googleauthorMin Yan-
dc.contributor.googleauthorZheng Gang Zhu-
dc.contributor.googleauthorSung Hoon Noh-
dc.identifier.doi10.1007/s11605-009-0800-3-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00572-
dc.contributor.localIdA02376-
dc.contributor.localIdA01281-
dc.contributor.localIdA04382-
dc.relation.journalcodeJ01418-
dc.identifier.eissn1873-4626-
dc.identifier.pmid19184612-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs11605-009-0800-3-
dc.subject.keywordAdvanced gastric cancer-
dc.subject.keywordTumor size-
dc.subject.keywordSurgical treatment-
dc.contributor.alternativeNameKim, Sung Soo-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNameOh, Sung Jin-
dc.contributor.alternativeNameHyung, Woo Jin-
dc.contributor.affiliatedAuthorKim, Sung Soo-
dc.contributor.affiliatedAuthorOh, Sung Jin-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorHyung, Woo Jin-
dc.citation.volume13-
dc.citation.number5-
dc.citation.startPage881-
dc.citation.endPage885-
dc.identifier.bibliographicCitationJOURNAL OF GASTROINTESTINAL SURGERY, Vol.13(5) : 881-885, 2009-
dc.identifier.rimsid42564-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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