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Incremental predictive value of pre-procedural N-terminal pro-B-type natriuretic peptide for short-term recurrence in atrial fibrillation ablation

DC Field Value Language
dc.contributor.author김성순-
dc.contributor.author김진배-
dc.contributor.author손정우-
dc.contributor.author심원흠-
dc.contributor.author이문형-
dc.contributor.author이병호-
dc.contributor.author장양수-
dc.contributor.author정남식-
dc.contributor.author정보영-
dc.contributor.author조승연-
dc.contributor.author황혜진-
dc.date.accessioned2015-04-24T17:10:15Z-
dc.date.available2015-04-24T17:10:15Z-
dc.date.issued2009-
dc.identifier.issn1861-0684-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104890-
dc.description.abstractThe objective of this work was to assess the predictive value of pre-procedural N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in patients undergoing atrial fibrillation (AF) ablation. Seventy-three consecutive patients with AF (paroxysmal n = 49, persistent n = 24) and preserved left ventricular (LV) systolic function (LV ejection fraction > 45%) were prospectively enrolled in this study. All of the enrolled patients underwent catheter ablation after a measurement of their plasma NT-proBNP levels, and an echocardiographic examination with assessment of their LV diastolic function and left atrial(LA) volume. Patients with AF recurrence at 3 months had more persistent AF (P = 0.001), a higher LA volume index (P = 0.002), lesser decelerating times (DT) of mitral inflow (P = 0.014), and higher NT-proBNP levels (P < 0.001), when compared with patients with sinus rhythm restoration. The baseline log NT-proBNP correlated significantly with age (r = 0.26, P = 0.025), LA volume index (r = 0.41, P = 0.001), E/E' (r = 0.34, P = 0.007), DT (r = -0.34, P = 0.007), and E (r = 0.25, P = 0.04). The log NT-proBNP (HR 7.76, 95% CI 2.95-20.39, P < 0.001) was an independent predictor of AF recurrence. The measurement of NT-proBNP added incremental predictive value to standard indexes of LA size or diastolic function, including LA volume index and DT (P = 0.02). This study suggests the clinical utility of the level of NT-proBNP as an integrating marker of various risk factors, and as an incremental predictive marker for AF catheter ablation.-
dc.description.statementOfResponsibilityopen-
dc.format.extent213~218-
dc.relation.isPartOfCLINICAL RESEARCH IN CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAtrial Fibrillation/blood-
dc.subject.MESHAtrial Fibrillation/physiopathology-
dc.subject.MESHAtrial Fibrillation/therapy*-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHCatheter Ablation/methods*-
dc.subject.MESHEchocardiography-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNatriuretic Peptide, Brain/blood*-
dc.subject.MESHPeptide Fragments/blood*-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHProspective Studies-
dc.subject.MESHRecurrence-
dc.subject.MESHRisk Factors-
dc.subject.MESHVentricular Function, Left-
dc.titleIncremental predictive value of pre-procedural N-terminal pro-B-type natriuretic peptide for short-term recurrence in atrial fibrillation ablation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorHye Jin Hwang-
dc.contributor.googleauthorJung Woo Son-
dc.contributor.googleauthorByung-Ho Nam-
dc.contributor.googleauthorBoyoung Joung-
dc.contributor.googleauthorByungho Lee-
dc.contributor.googleauthorJin-Bae Kim-
dc.contributor.googleauthorMoon-Hyoung Lee-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorNamsik Chung-
dc.contributor.googleauthorWon-Heum Shim-
dc.contributor.googleauthorSeung-Yun Cho-
dc.contributor.googleauthorSung Soon Kim-
dc.identifier.doi10.1007/s00392-009-0744-3-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00573-
dc.contributor.localIdA01016-
dc.contributor.localIdA01991-
dc.contributor.localIdA02202-
dc.contributor.localIdA02766-
dc.contributor.localIdA03448-
dc.contributor.localIdA03585-
dc.contributor.localIdA03609-
dc.contributor.localIdA03844-
dc.contributor.localIdA04496-
dc.contributor.localIdA02800-
dc.relation.journalcodeJ03070-
dc.identifier.eissn1861-0692-
dc.identifier.pmid19229464-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00392-009-0744-3-
dc.subject.keywordatrial fibrillation-
dc.subject.keywordcatheter ablation-
dc.subject.keywordNT-proBNP-
dc.contributor.alternativeNameKim, Sung Soon-
dc.contributor.alternativeNameKim, Jin Bae-
dc.contributor.alternativeNameSon, Jung Woo-
dc.contributor.alternativeNameShim, Won Heum-
dc.contributor.alternativeNameLee, Moon Hyoung-
dc.contributor.alternativeNameLee, Byung Ho-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameJoung, Bo Young-
dc.contributor.alternativeNameCho, Seung Yun-
dc.contributor.alternativeNameHwang, Hye Jin-
dc.contributor.affiliatedAuthorKim, Sung Soon-
dc.contributor.affiliatedAuthorKim, Jin Bae-
dc.contributor.affiliatedAuthorSon, Jung Woo-
dc.contributor.affiliatedAuthorShim, Won Heum-
dc.contributor.affiliatedAuthorLee, Moon Hyoung-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorJoung, Bo Young-
dc.contributor.affiliatedAuthorCho, Seung Yun-
dc.contributor.affiliatedAuthorHwang, Hye Jin-
dc.contributor.affiliatedAuthorLee, Byung Ho-
dc.citation.volume98-
dc.citation.number4-
dc.citation.startPage213-
dc.citation.endPage218-
dc.identifier.bibliographicCitationCLINICAL RESEARCH IN CARDIOLOGY, Vol.98(4) : 213-218, 2009-
dc.identifier.rimsid42553-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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