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Prognosis of pN3 stage gastric cancer

DC FieldValueLanguage
dc.contributor.author형우진-
dc.contributor.author홍민희-
dc.contributor.author김찬-
dc.contributor.author김혜련-
dc.contributor.author노성훈-
dc.contributor.author라선영-
dc.contributor.author안정련-
dc.contributor.author이성숙-
dc.contributor.author전홍재-
dc.contributor.author정민규-
dc.contributor.author정현철-
dc.contributor.author정희철-
dc.date.accessioned2015-04-24T17:09:09Z-
dc.date.available2015-04-24T17:09:09Z-
dc.date.issued2009-
dc.identifier.issn1598-2998-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104857-
dc.description.abstractPURPOSE: The aim of this study was to determine the prognosis of pN3 stage gastric cancer patients after they have undergone curative resection, and we also wanted to identify the prognostic factors according to the clinico-pathologic features. MATERIALS AND METHODS: Between January 2000 and December 2004, we retrospectively reviewed the medical records of the patients with histologically confirmed pN3 stage gastric cancer. They underwent both gastrectomy and lymphadenectomy with a curative aim. We categorized the pN3 stage patients into 2 groups; one with pN3 only (pN3M0) and the other with pN3 combined with M1 stage (pN3M1) that included peritoneal seeding, hepatic metastasis or para-aortic LN metastasis. RESULTS: Out of 467 patients with stage IV gastric adenocarcinoma who received surgery, 260 patients underwent curative resection and they were pathologically staged as N3. Among these 260 patients, 78 patients were classified as the pN3/M1 stage. For all the patients, the median follow-up period was 19 months (range: 1~108 months) and the median overall survival time was 16.2 months (95% CI, 14.1~18.3%). The 5-year survival rate of the pN3/M0 group was significantly higher than that of the pN3/M1 group (12.6% vs. 2.6%, respectively, p<0.0001). The identified predictor for a worse prognosis was an advanced T4 stage (HR: 3.38, 95% CI, 1.4~8.3, p=0.008) for the pN3 patients. CONCLUSION: The survival for the pN3 gastric cancer patients after curative gastrectomy was significantly longer in the pN3/M0 group as compared to that of the pN3/M1 group. An advanced T stage was a predictor for a poor prognosis for the pN3 patients. Therefore, diverse treatment strategies for these heterogeneous pN3 gastric cancer patients are needed for improving their survival-
dc.description.statementOfResponsibilityopen-
dc.format.extent73~79-
dc.relation.isPartOfCANCER RESEARCH AND TREATMENT-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titlePrognosis of pN3 stage gastric cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorJung Ryun Ahn-
dc.contributor.googleauthorMinkyu Jung-
dc.contributor.googleauthorChan Kim-
dc.contributor.googleauthorMin Hee Hong-
dc.contributor.googleauthorHong Jae Chon-
dc.contributor.googleauthorHye Ryun Kim-
dc.contributor.googleauthorHei-Cheul Jeung-
dc.contributor.googleauthorWoo Jin Hyung-
dc.contributor.googleauthorSung Sook Lee-
dc.contributor.googleauthorHyun Cheol Chung-
dc.contributor.googleauthorSung Hoon Noh-
dc.contributor.googleauthorSun Young Rha-
dc.identifier.doi10.4143/crt.2009.41.2.73-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04382-
dc.contributor.localIdA04393-
dc.contributor.localIdA01034-
dc.contributor.localIdA01166-
dc.contributor.localIdA01281-
dc.contributor.localIdA02256-
dc.contributor.localIdA02867-
dc.contributor.localIdA03565-
dc.contributor.localIdA03606-
dc.contributor.localIdA03773-
dc.contributor.localIdA03794-
dc.contributor.localIdA01316-
dc.relation.journalcodeJ00453-
dc.identifier.eissn2005-9256-
dc.identifier.pmid19707504-
dc.subject.keywordAdvanced gastric cancer-
dc.subject.keywordPrognosis-
dc.subject.keywordPrognostic factor-
dc.subject.keywordSurvival-
dc.subject.keywordpN3-
dc.contributor.alternativeNameHyung, Woo Jin-
dc.contributor.alternativeNameHong, Min Hee-
dc.contributor.alternativeNameKim, Chan-
dc.contributor.alternativeNameKim, Hye Ryun-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNameRha, Sun Young-
dc.contributor.alternativeNameAhn, Jung Ryun-
dc.contributor.alternativeNameLee, Sung Sook-
dc.contributor.alternativeNameChon, Hong Jae-
dc.contributor.alternativeNameJung, Min Kyu-
dc.contributor.alternativeNameChung, Hyun Cheol-
dc.contributor.alternativeNameJeung, Hei Cheul-
dc.contributor.affiliatedAuthorHyung, Woo Jin-
dc.contributor.affiliatedAuthorHong, Min Hee-
dc.contributor.affiliatedAuthorKim, Chan-
dc.contributor.affiliatedAuthorKim, Hye Ryun-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorAhn, Jung Ryun-
dc.contributor.affiliatedAuthorLee, Sung Sook-
dc.contributor.affiliatedAuthorChon, Hong Jae-
dc.contributor.affiliatedAuthorJung, Min Kyu-
dc.contributor.affiliatedAuthorChung, Hyun Cheol-
dc.contributor.affiliatedAuthorJeung, Hei Cheul-
dc.contributor.affiliatedAuthorRha, Sun Young-
dc.citation.volume41-
dc.citation.number2-
dc.citation.startPage73-
dc.citation.endPage79-
dc.identifier.bibliographicCitationCANCER RESEARCH AND TREATMENT, Vol.41(2) : 73-79, 2009-
dc.identifier.rimsid42526-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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