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Beneficial effects of microwave-induced argon plasma treatment on cellular behaviors of articular chondrocytes onto nanofibrous silk fibroin mesh

Authors
 Soo Chang Jin  ;  Hyun Sook Baek  ;  Yeon I Woo  ;  Mi Hee Lee  ;  Jung-Sung Kim  ;  Jong-Chul Park  ;  Young Hwan Park  ;  Dong Kyun Rah  ;  Kie-Hyung Chung  ;  Seung Jin Lee  ;  In Ho Han 
Citation
 MACROMOLECULAR RESEARCH, Vol.17(9) : 703-708, 2009 
Journal Title
 MACROMOLECULAR RESEARCH 
ISSN
 1598-5032 
Issue Date
2009
Keywords
nanofibrous silk fibroin ; chondrocytes ; cartilage ; microwave-induced argon plasma ; cytocompatibility.
Abstract
Silk fibroin scaffolds were examined as a biomaterial option for tissue-engineered cartilage-like tissue. In tissue engineering for cartilage repair using a scaffold, initial chondrocyte-material interactions are important for the following cell behaviors. In this study, the surface of nanofibrous silk fibroin (NSF) meshes was modified by a microwave-induced argon plasma treatment in order to improve the cytocompatibility of the meshes used as cartilaginous grafts. In addition, the effects of a plasma treatment on the cellular behavior of chondrocytes on NSF were examined. The plasma treatment resulted in an increase in the hydrophilicity of NSF meshes suggesting that the cytocompatibility of the mesh might be improved. Furthermore, the human articular chondrocytes showed higher viability on the surface-modified NSF meshes. These results suggest that the surface modification of NSF meshes by plasma can enhance the cellular behavior of chondrocytes and may be used in tissue engineering
Full Text
http://link.springer.com/article/10.1007%2FBF03218931#
DOI
10.1007/BF03218931
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
Yonsei Authors
Rah, Dong Kyun(나동균)
Park, Jong Chul(박종철) ORCID logo https://orcid.org/0000-0003-0083-5991
Woo, Yeon I.(우연이)
Lee, Mi Hee(이미희) ORCID logo https://orcid.org/0000-0002-9630-7044
Jin, Soo Chang(진수창)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/104720
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