Cited 62 times in
Uric acid is associated with the rate of residual renal function decline in peritoneal dialysis patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강신욱 | - |
dc.contributor.author | 김동기 | - |
dc.contributor.author | 김현욱 | - |
dc.contributor.author | 박선영 | - |
dc.contributor.author | 박정탁 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 장제현 | - |
dc.contributor.author | 장태익 | - |
dc.contributor.author | 한대석 | - |
dc.date.accessioned | 2015-04-24T17:03:18Z | - |
dc.date.available | 2015-04-24T17:03:18Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0931-0509 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/104673 | - |
dc.description.abstract | BACKGROUND: Uric acid (UA) is known to play a pathogenic role in chronic kidney disease (CKD). However, its effect in end-stage renal disease (ESRD) has not yet been elucidated. We explored the prevalence of hyperuricaemia and the relationship between UA and residual renal function (RRF) in peritoneal dialysis (PD) patients. METHODS: The subjects of this study were 134 PD patients who started dialysis at the Yonsei University Health System between January 2000 and December 2005. Timed urine collections were performed within 1 month of PD commencement and at 6-month intervals thereafter. The slope of decline of RRF over time was calculated by linear regression analysis of serial urinary urea and creatinine clearances for each patient. Biochemical and clinical data at the time of initial urine collection were considered as baseline. RESULTS: At baseline, 32.8% of the PD patients had hyperuricaemia (UA >or=7.0 mg/dl). A significant majority of patients with hyperuricaemia were diabetic (P = 0.02). Hypertensive patients had a higher UA level (P = 0.002) compared to normotensive patients. The overall reduction rate of RRF in hyperuricaemic patients was significantly higher than in the normouricaemic group (P = 0.001). In the multiple linear regression analysis, hyperuricaemia and history of DM showed a significant negative correlation with the reduction rate of RRF after adjusting for demographic data, comorbid conditions, body mass index, baseline RRF and medications (P = 0.001). CONCLUSIONS: Hyperuricaemia is common among PD patients and is significantly associated with the rate of decline of RRF | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | NEPHROLOGY DIALYSIS TRANSPLANTATION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension/blood | - |
dc.subject.MESH | Hyperuricemia/epidemiology* | - |
dc.subject.MESH | Kidney/physiopathology* | - |
dc.subject.MESH | Kidney Failure, Chronic/blood | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Peritoneal Dialysis, Continuous Ambulatory* | - |
dc.subject.MESH | Uric Acid/blood | - |
dc.title | Uric acid is associated with the rate of residual renal function decline in peritoneal dialysis patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jung Tak Park | - |
dc.contributor.googleauthor | Dong Ki Kim | - |
dc.contributor.googleauthor | Tae Ik Chang | - |
dc.contributor.googleauthor | Hyun Wook Kim | - |
dc.contributor.googleauthor | Jae Hyun Chang | - |
dc.contributor.googleauthor | Sun Young Park | - |
dc.contributor.googleauthor | Eunyoung Kim | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Dae-Suk Han | - |
dc.contributor.googleauthor | Tae-Hyun Yoo | - |
dc.identifier.doi | 10.1093/ndt/gfp272 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A01126 | - |
dc.contributor.localId | A01654 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A03469 | - |
dc.contributor.localId | A03486 | - |
dc.contributor.localId | A04272 | - |
dc.contributor.localId | A00811 | - |
dc.contributor.localId | A01499 | - |
dc.contributor.localId | A00400 | - |
dc.relation.journalcode | J02316 | - |
dc.identifier.eissn | 1460-2385 | - |
dc.identifier.pmid | 19491381 | - |
dc.subject.keyword | end stage renal disease | - |
dc.subject.keyword | hypertension | - |
dc.subject.keyword | peritoneal dialysis | - |
dc.subject.keyword | residual renal function | - |
dc.subject.keyword | uric acid | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.alternativeName | Kim, Dong Ki | - |
dc.contributor.alternativeName | Kim, Eun Young | - |
dc.contributor.alternativeName | Kim, Hyun Wook | - |
dc.contributor.alternativeName | Park, Sun Young | - |
dc.contributor.alternativeName | Park, Jung Tak | - |
dc.contributor.alternativeName | Yoo, Tae Hyun | - |
dc.contributor.alternativeName | Chang, Jae Hyun | - |
dc.contributor.alternativeName | Chang, Tae Ik | - |
dc.contributor.alternativeName | Han, Dae Suk | - |
dc.contributor.affiliatedAuthor | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Wook | - |
dc.contributor.affiliatedAuthor | Park, Jung Tak | - |
dc.contributor.affiliatedAuthor | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | Chang, Jae Hyun | - |
dc.contributor.affiliatedAuthor | Chang, Tae Ik | - |
dc.contributor.affiliatedAuthor | Han, Dae Suk | - |
dc.contributor.affiliatedAuthor | Kim, Eun Young | - |
dc.contributor.affiliatedAuthor | Park, Sun Young | - |
dc.contributor.affiliatedAuthor | Kim, Dong Ki | - |
dc.citation.volume | 24 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 3520 | - |
dc.citation.endPage | 3525 | - |
dc.identifier.bibliographicCitation | NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol.24(11) : 3520-3525, 2009 | - |
dc.identifier.rimsid | 52850 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.