Cited 33 times in
The prognostic impact of the number of lymph nodes retrieved after neoadjuvant chemoradiotherapy with mesorectal excision for rectal cancer
DC Field | Value | Language |
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dc.contributor.author | 금기창 | - |
dc.contributor.author | 김남규 | - |
dc.contributor.author | 김호근 | - |
dc.contributor.author | 민병소 | - |
dc.contributor.author | 손승국 | - |
dc.contributor.author | 안중배 | - |
dc.contributor.author | 이강영 | - |
dc.contributor.author | 조장환 | - |
dc.date.accessioned | 2015-04-24T17:00:38Z | - |
dc.date.available | 2015-04-24T17:00:38Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0022-4790 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/104590 | - |
dc.description.abstract | BACKGROUND: We aimed to assess factors associated with the number of nodes retrieved and the impact of the number of lymph nodes in rectal cancer patients who underwent neoadjuvant chemoradiation with radical surgery. METHODS: A total of 258 patients were enrolled. Lymph nodes were retrieved from specimens using a manual dissection technique. RESULTS: Of the 258 patients, nine patients had an absence of lymph nodes (ypNx), 150 patients had a node-negative status (ypN(-)) and 99 patients had node-positive disease (ypN(+)). An advanced ypT classification (ypT3,4) and larger tumor (>4 cm) were associated with an increased number of nodes retrieved. The pretreatment CEA level (>5 ng/ml) and ypN(+) classification were significant risk factors for cancer specific and recurrence free survival. There was no significant difference of oncological outcomes among ypNx patients and a subset of ypN(-) patients based on the number of nodes retrieved using three cutoff values (1-11, 12-25, and 25-65 nodes). CONCLUSIONS: In a neoadjuvant setting, ypN(+) disease was an independent risk factor for oncological outcomes. An absence of nodes does not represent an inferior oncological outcome. The number of nodes does not seen to impact survival and recurrence in ypN(-) patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1~7 | - |
dc.relation.isPartOf | JOURNAL OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymph Node Excision* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Rectal Neoplasms/mortality | - |
dc.subject.MESH | Rectal Neoplasms/pathology | - |
dc.subject.MESH | Rectal Neoplasms/surgery* | - |
dc.subject.MESH | Survival Rate | - |
dc.title | The prognostic impact of the number of lymph nodes retrieved after neoadjuvant chemoradiotherapy with mesorectal excision for rectal cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | YOUNG-WAN KIM | - |
dc.contributor.googleauthor | NAM-KYU KIM | - |
dc.contributor.googleauthor | BYUNG-SOH MIN | - |
dc.contributor.googleauthor | KANG-YOUNG LEE | - |
dc.contributor.googleauthor | SEUNG-KOOK SOHN | - |
dc.contributor.googleauthor | CHANG-HWAN CHO | - |
dc.contributor.googleauthor | HOGUEN KIM | - |
dc.contributor.googleauthor | KI-CHANG KEUM | - |
dc.contributor.googleauthor | JUNG-BAI AHN | - |
dc.identifier.doi | 10.1002/jso.21299 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00272 | - |
dc.contributor.localId | A00353 | - |
dc.contributor.localId | A01183 | - |
dc.contributor.localId | A01402 | - |
dc.contributor.localId | A01978 | - |
dc.contributor.localId | A02262 | - |
dc.contributor.localId | A02640 | - |
dc.contributor.localId | A03894 | - |
dc.relation.journalcode | J01762 | - |
dc.identifier.eissn | 1096-9098 | - |
dc.identifier.pmid | 19418495 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/jso.21299/abstract | - |
dc.subject.keyword | rectal neoplasm | - |
dc.subject.keyword | retrieved lymph node | - |
dc.subject.keyword | neoadjuvant chemoradiation | - |
dc.subject.keyword | mesorectal excision | - |
dc.contributor.alternativeName | Keum, Ki Chang | - |
dc.contributor.alternativeName | Kim, Nam Kyu | - |
dc.contributor.alternativeName | Kim, Ho Keun | - |
dc.contributor.alternativeName | Min, Byung Soh | - |
dc.contributor.alternativeName | Sohn, Seung Kook | - |
dc.contributor.alternativeName | Ahn, Joong Bae | - |
dc.contributor.alternativeName | Lee, Kang Young | - |
dc.contributor.alternativeName | Cho, Chang Hwan | - |
dc.contributor.affiliatedAuthor | Keum, Ki Chang | - |
dc.contributor.affiliatedAuthor | Kim, Nam Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Ho Keun | - |
dc.contributor.affiliatedAuthor | Min, Byung Soh | - |
dc.contributor.affiliatedAuthor | Sohn, Seung Kook | - |
dc.contributor.affiliatedAuthor | Ahn, Joong Bae | - |
dc.contributor.affiliatedAuthor | Lee, Kang Young | - |
dc.contributor.affiliatedAuthor | Cho, Chang Hwan | - |
dc.citation.volume | 100 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 7 | - |
dc.identifier.bibliographicCitation | JOURNAL OF SURGICAL ONCOLOGY, Vol.100(1) : 1-7, 2009 | - |
dc.identifier.rimsid | 51126 | - |
dc.type.rims | ART | - |
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