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Incidence and risk factors of infection in a single cohort of 110 adults with systemic lupus erythematosus

DC FieldValueLanguage
dc.contributor.author김준명-
dc.contributor.author김창오-
dc.contributor.author백지현-
dc.contributor.author송영구-
dc.contributor.author이한성-
dc.contributor.author정수진-
dc.contributor.author진범식-
dc.contributor.author최준용-
dc.contributor.author최희경-
dc.contributor.author한상훈-
dc.date.accessioned2015-04-24T16:54:47Z-
dc.date.available2015-04-24T16:54:47Z-
dc.date.issued2009-
dc.identifier.issn0036-5548-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104407-
dc.description.abstractInfection is a major cause of mortality in patients with systemic lupus erythematosus (SLE). This study describes infectious complications in SLE patients and analyzes the risk factors for infection at the time of SLE diagnosis and during the course of SLE in a case-control study. Of 110 patients enrolled, 42 (38%) had at least 1 episode of infectious disease. The incidence of infectious disease was 4.4/100 patient-years (py) with a total follow-up duration of 954 y. In multivariate analysis, independent predictors of infection at the time of SLE diagnosis were an SLE disease activity index (SLEDAI) > 12 (p = 0.01), C3 levels < 90 mg/dl (p = 0.01) and positive anti-ds DNA antibodies (p < 0.01). Frequent flare-ups (p = 0.04) and follow-up duration > or =8 y (p = 0.023) were also significant risk factors for infectious diseases. It is mandatory to closely observe SLE patients with risk factors for developing infectious diseases.-
dc.description.statementOfResponsibilityopen-
dc.format.extent268~274-
dc.relation.isPartOfSCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAntibodies, Antinuclear/blood-
dc.subject.MESHCase-Control Studies-
dc.subject.MESHCommunicable Diseases/epidemiology*-
dc.subject.MESHCommunicable Diseases/etiology*-
dc.subject.MESHComplement C3/analysis-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHLupus Erythematosus, Systemic/complications*-
dc.subject.MESHMale-
dc.subject.MESHMedical Records-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.titleIncidence and risk factors of infection in a single cohort of 110 adults with systemic lupus erythematosus-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSU JIN JEONG-
dc.contributor.googleauthorHEEKYUNG CHOI-
dc.contributor.googleauthorHAN SUNG LEE-
dc.contributor.googleauthorSANG HOON HAN-
dc.contributor.googleauthorBUM SIK CHIN-
dc.contributor.googleauthorJI-HYEON BAEK-
dc.contributor.googleauthorCHANG OH KIM-
dc.contributor.googleauthorJUN YONG CHOI-
dc.contributor.googleauthorYOUNG GOO SONG-
dc.contributor.googleauthorJUNE MYUNG KIM-
dc.identifier.doi10.1080/00365540902744741-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00953-
dc.contributor.localIdA01044-
dc.contributor.localIdA01839-
dc.contributor.localIdA02037-
dc.contributor.localIdA03277-
dc.contributor.localIdA03638-
dc.contributor.localIdA03981-
dc.contributor.localIdA04191-
dc.contributor.localIdA04228-
dc.contributor.localIdA04286-
dc.relation.journalcodeJ02634-
dc.identifier.eissn1651-1980-
dc.identifier.pmid19172435-
dc.identifier.urlhttp://informahealthcare.com/doi/abs/10.1080/00365540902744741-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameKim, Chang Oh-
dc.contributor.alternativeNameBaek, Ji Hyeon-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameLee, Han Sung-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameChin, Bum Sik-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameChoi, Hee Kyoung-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorKim, Chang Oh-
dc.contributor.affiliatedAuthorBaek, Ji Hyeon-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorLee, Han Sung-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorChin, Bum Sik-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorChoi, Hee Kyoung-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.citation.volume41-
dc.citation.number4-
dc.citation.startPage268-
dc.citation.endPage274-
dc.identifier.bibliographicCitationSCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, Vol.41(4) : 268-274, 2009-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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