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The history of ependymoma management

DC Field Value Language
dc.contributor.author김동석-
dc.contributor.author심규원-
dc.contributor.author최중언-
dc.date.accessioned2015-04-24T16:49:02Z-
dc.date.available2015-04-24T16:49:02Z-
dc.date.issued2009-
dc.identifier.issn0256-7040-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104227-
dc.description.abstractINTRODUCTION: the ependymomas are relatively not a common tumor. However, most clinicians agree that the radical removal of the tumor is the most important prognostic factor. MORBIDITY of TREATMENT: Tumor removal was not sufficient before the era of magnetic resonance imaging (MRI) and resulted in a considerable operative morbidity and mortality. As the microneurosurgical techniques and microsurgical anatomy become popular and the MRI provide more detailed anatomical information preoperatively, radical removal of this complex and complicated tumor can be more feasible. in childhood ependymoma, the treatment-related morbidity and mortality can be the special issues, which can modify the policy of management safe tumor removal and minimal adjuvant treatment, which are extremely important. RADIATION THERAPY: Radiation treatment has been the option for disseminated disease and residual tumor. With the advancement of detailed MR anatomical information, safer and more delicate radiation becomes possible with newer radiation modalities, three-dimensional conformal radiotherapy, intensity modulating radiotherapy, and tomotherapy. PROGNOSTIC FACTORS: Although many clinicians believe that the ependymomas are inheritably chemoresistant, the new targets for the treatment are under investigation or clinically tried. Also, the genetic alterations of ependymoma are developing and might be a promising target. CONCLUSION: the surgical techniques and assistant modalities for tumor removal are still advancing. So, the outcome of ependymoma is still improving. Unfortunately, newer treatment modalities, such as new chemotherapeutic agent and gene modification agent, are still not promising. the history of ependymoma management is still in progress.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1167~1183-
dc.relation.isPartOfCHILDS NERVOUS SYSTEM-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBrain Neoplasms/diagnosis-
dc.subject.MESHBrain Neoplasms/mortality-
dc.subject.MESHBrain Neoplasms/therapy-
dc.subject.MESHChild-
dc.subject.MESHDrug Therapy/mortality-
dc.subject.MESHEpendymoma/diagnosis*-
dc.subject.MESHEpendymoma/mortality-
dc.subject.MESHEpendymoma/therapy*-
dc.subject.MESHHumans-
dc.subject.MESHNeurosurgical Procedures/mortality-
dc.subject.MESHPrognosis-
dc.subject.MESHRadiotherapy/mortality-
dc.subject.MESHSpinal Cord Neoplasms/diagnosis-
dc.subject.MESHSpinal Cord Neoplasms/mortality-
dc.subject.MESHSpinal Cord Neoplasms/therapy-
dc.titleThe history of ependymoma management-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학)-
dc.contributor.googleauthorKyu-Won Shim-
dc.contributor.googleauthorDong-Seok Kim-
dc.contributor.googleauthorJoong-Uhn Choi-
dc.identifier.doi10.1007/s00381-009-0900-0-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00402-
dc.contributor.localIdA02187-
dc.contributor.localIdA04194-
dc.relation.journalcodeJ00525-
dc.identifier.eissn1433-0350-
dc.identifier.pmid19458954-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00381-009-0900-0-
dc.subject.keywordEpendymoma-
dc.subject.keywordManagement-
dc.subject.keywordHistory-
dc.subject.keywordCraniospinal irradiation-
dc.subject.keywordChemotherapy-
dc.contributor.alternativeNameKim, Dong Seok-
dc.contributor.alternativeNameShim, Kyu Won-
dc.contributor.alternativeNameChoi, Joong Uhn-
dc.contributor.affiliatedAuthorKim, Dong Seok-
dc.contributor.affiliatedAuthorShim, Kyu Won-
dc.contributor.affiliatedAuthorChoi, Joong Uhn-
dc.citation.volume25-
dc.citation.number10-
dc.citation.startPage1167-
dc.citation.endPage1183-
dc.identifier.bibliographicCitationCHILDS NERVOUS SYSTEM, Vol.25(10) : 1167-1183, 2009-
dc.identifier.rimsid56124-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

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