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이차 관해 후 Gemtuzumab Ozogamicin (MylotargⓇ) 단독 공고요법으로 장기 무질병 생존 중인 급성골수구성백혈병 1례: 종교적인 이유로 수혈과 조혈모세포 이식이 불가능하였던 예
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권승연 | - |
dc.contributor.author | 김효선 | - |
dc.contributor.author | 양우익 | - |
dc.contributor.author | 원성철 | - |
dc.contributor.author | 유철주 | - |
dc.date.accessioned | 2015-04-24T16:45:21Z | - |
dc.date.available | 2015-04-24T16:45:21Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1225-6978 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/104111 | - |
dc.description.abstract | Despite improvement of long-term survival rate in pediatric acute myeloid leukemia (AML) during the last two decades, relapse/refractory disease remains a major obstacle to further improvement of prognosis. Moreover, there are only few therapeutic options which stimulate investigations for targeted, less toxic therapy. Gemtuzumab ozogamicin (GO, MylotargⓇ) is an anti-CD33 monoclonal antibody and there are ongoing studies evaluating safety and efficacy of this drug in relapsed/refractory AML patients. Still, the response rate is only 30% and the response does not last more than a year. We present a case of pediatric central nervous system relapsed AML who was treated with GO as a single consolidation therapy without stem cell transplantation because of religious belief and maintained CR status for more than 3 years. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 59~64 | - |
dc.relation.isPartOf | Clinical Pediatric Hematology-Oncology (임상소아혈액종양) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 이차 관해 후 Gemtuzumab Ozogamicin (MylotargⓇ) 단독 공고요법으로 장기 무질병 생존 중인 급성골수구성백혈병 1례: 종교적인 이유로 수혈과 조혈모세포 이식이 불가능하였던 예 | - |
dc.title.alternative | Gemtuzumab Ozogamicin (MylotargⓇ) as a Single Consolidation Therapy in Relapsed Pediatric Acute Myeloid Leukemia Patient: a Patient Who Refused Transfusion and Stem Cell Transplantation for Religious Belief | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | 이하늘 | - |
dc.contributor.googleauthor | 김효선 | - |
dc.contributor.googleauthor | 권승연 | - |
dc.contributor.googleauthor | 원성철 | - |
dc.contributor.googleauthor | 김범식 | - |
dc.contributor.googleauthor | 최성열 | - |
dc.contributor.googleauthor | 양우익 | - |
dc.contributor.googleauthor | 유철주 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00226 | - |
dc.contributor.localId | A01201 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A02434 | - |
dc.contributor.localId | A02524 | - |
dc.relation.journalcode | J00606 | - |
dc.subject.keyword | Pediatric | - |
dc.subject.keyword | Acute myeloid leukemia | - |
dc.subject.keyword | Gemtuzumab ozogamicin | - |
dc.subject.keyword | Mylotarg | - |
dc.contributor.alternativeName | Kwon, Seung Yeon | - |
dc.contributor.alternativeName | Kim, Hyo Sun | - |
dc.contributor.alternativeName | Yang, Woo Ick | - |
dc.contributor.alternativeName | Won, Sung Chul | - |
dc.contributor.alternativeName | Lyu, Chuhl Joo | - |
dc.contributor.affiliatedAuthor | Kwon, Seung Yeon | - |
dc.contributor.affiliatedAuthor | Kim, Hyo Sun | - |
dc.contributor.affiliatedAuthor | Yang, Woo Ick | - |
dc.contributor.affiliatedAuthor | Won, Sung Chul | - |
dc.contributor.affiliatedAuthor | Lyu, Chuhl Joo | - |
dc.citation.volume | 16 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 59 | - |
dc.citation.endPage | 64 | - |
dc.identifier.bibliographicCitation | Clinical Pediatric Hematology-Oncology (임상소아혈액종양), Vol.16(1) : 59-64, 2009 | - |
dc.identifier.rimsid | 54553 | - |
dc.type.rims | ART | - |
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