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Prediction of recurrence of early gastric cancer after curative resection

DC FieldValueLanguage
dc.contributor.author김기열-
dc.contributor.author김성수-
dc.contributor.author노성훈-
dc.contributor.author라선영-
dc.contributor.author오성진-
dc.contributor.author이찬주-
dc.contributor.author정현철-
dc.contributor.author최승호-
dc.date.accessioned2015-04-24T16:43:18Z-
dc.date.available2015-04-24T16:43:18Z-
dc.date.issued2009-
dc.identifier.issn1068-9265-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104047-
dc.description.abstractBACKGROUND: Recurrence of early gastric cancer (EGC) after curative resection is rare, and the types of EGC that may recur have not been well studied. We attempted to create a system for predicting recurrence of EGC after R0 resection. METHODS: From January 1987 to April 2005, 2,923 patients with EGC who underwent curative resection were retrospectively studied. Of them, 79 patients (2.7%) experienced recurrence. Logistic regression was performed to identify independent risk factors for overall recurrence and early recurrence (recurred within 24 months after resection) of EGC. A nomogram was developed on the basis of a Cox regression. RESULTS: Median time to recurrence was 20.5 months, and early recurrence accounted for 60.7% of instances. Presence of lymph node metastasis and elevated gross type were independent risk factors for overall recurrence; patients with both identified risk factors had a higher recurrence rate than average level (17.5% vs. 2.7%, P < 0.001). Meanwhile, male gender, elevated gross type, and presence of lymph node metastasis were significantly associated with early recurrence, and in patients with all of the aforementioned identified risk factors, the early recurrence rate was higher (12.2% vs. 1.6%, P < 0.001). A nomogram for predicting the disease-free survival after operation was constructed. Its c-index was 0.79 and it appeared to be accurate. CONCLUSIONS: Recurrence of EGC after curative resection can be predicted by using common clinical characteristics. Patients at high risk of overall and early recurrence could be identified; individual disease-free survival was predictable by the internally validated nomogram-
dc.description.statementOfResponsibilityopen-
dc.format.extent1896~1902-
dc.relation.isPartOfANNALS OF SURGICAL ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHFemale-
dc.subject.MESHGastrectomy-
dc.subject.MESHHumans-
dc.subject.MESHLymph Nodes/pathology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Recurrence, Local-
dc.subject.MESHNomograms-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPrognosis-
dc.subject.MESHRegression Analysis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStomach Neoplasms/pathology*-
dc.subject.MESHStomach Neoplasms/surgery*-
dc.subject.MESHYoung Adult-
dc.titlePrediction of recurrence of early gastric cancer after curative resection-
dc.typeArticle-
dc.contributor.collegeResearcher Institutes (부설 연구소)-
dc.contributor.departmentOral Cancer Research Institute (구강종양연구소)-
dc.contributor.googleauthorJi Fu Lai-
dc.contributor.googleauthorSungsoo Kim-
dc.contributor.googleauthorKiyeol Kim-
dc.contributor.googleauthorChen Li-
dc.contributor.googleauthorSung Jin Oh-
dc.contributor.googleauthorWoo Jin Hyung-
dc.contributor.googleauthorSun Young Rha-
dc.contributor.googleauthorHyun Cheol Chung-
dc.contributor.googleauthorSeung Ho Choi-
dc.contributor.googleauthorLin Bo Wang-
dc.contributor.googleauthorSung Hoon Noh-
dc.identifier.doi10.1245/s10434-009-0473-x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00337-
dc.contributor.localIdA01281-
dc.contributor.localIdA03773-
dc.contributor.localIdA04102-
dc.contributor.localIdA00572-
dc.contributor.localIdA02376-
dc.contributor.localIdA01316-
dc.contributor.localIdA03238-
dc.relation.journalcodeJ00179-
dc.identifier.eissn1534-4681-
dc.identifier.pmid19434457-
dc.identifier.urlhttp://link.springer.com/article/10.1245%2Fs10434-009-0473-x-
dc.contributor.alternativeNameKim, Ki Yeol-
dc.contributor.alternativeNameKim, Sung Soo-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNameRha, Sun Young-
dc.contributor.alternativeNameOh, Sung Jin-
dc.contributor.alternativeNameLee, Chan Joo-
dc.contributor.alternativeNameChung, Hyun Cheol-
dc.contributor.alternativeNameChoi, Seung Ho-
dc.contributor.affiliatedAuthorKim, Ki Yeol-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorChung, Hyun Cheol-
dc.contributor.affiliatedAuthorChoi, Seung Ho-
dc.contributor.affiliatedAuthorKim, Sung Soo-
dc.contributor.affiliatedAuthorOh, Sung Jin-
dc.contributor.affiliatedAuthorRha, Sun Young-
dc.contributor.affiliatedAuthorLee, Chan Joo-
dc.citation.volume16-
dc.citation.number7-
dc.citation.startPage1896-
dc.citation.endPage1902-
dc.identifier.bibliographicCitationANNALS OF SURGICAL ONCOLOGY, Vol.16(7) : 1896-1902, 2009-
dc.identifier.rimsid46791-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Others (기타) > 1. Journal Papers

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