Cited 6 times in
A single dose of esmolol blunts the increase in bispectral index to tracheal intubation during sevoflurane but not desflurane anesthesia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 민경태 | - |
dc.contributor.author | 김종훈 | - |
dc.contributor.author | 최승호 | - |
dc.date.accessioned | 2015-04-24T16:41:53Z | - |
dc.date.available | 2015-04-24T16:41:53Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0898-4921 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/104003 | - |
dc.description.abstract | Activation of the peripheral nerve system by endotracheal intubation is accompanied by an increase in bispectral index (BIS). Esmolol produces a dose-dependent attenuation of the adrenergic response to endotracheal intubation. Desflurane increases sympathetic nerve activity and plasma norepinephrine relative to sevoflurane. The authors hypothesized that esmolol might blunt the BIS response to endotracheal intubation more during sevoflurane anesthesia than desflurane anesthesia. In this double blind, randomized study, after the induction of anesthesia, patients were mask-ventilated with either sevoflurane or desflurane (end-tidal 1 minimum alveolar concentration) and received normal saline or esmolol (0.5 mg/kg) 1 minute before intubation (sevoflurane-control, sevoflurane-esmolol, desflurane-control, and desflurane-esmolol groups, n=20/group). BIS, mean arterial pressure, and heart rate were measured before the induction of anesthesia (awake), before esmolol injection (time point -1), immediately before intubation (time point 0), and every minute for 5 minutes after tracheal intubation (time point 1 to 5). Compared with preintubation, esmolol attenuated the increase in BIS at 1 minute after intubation during sevoflurane anesthesia (5.1% for esmolol and 31.7% for control) but not during desflurane anesthesia (28.6% for esmolol and 30.8% for control). Mean arterial pressure and heart rate increased after intubation in all groups but the changes were greater in the control groups than the esmolol groups. In conclusion, a single dose of esmolol blunted the increase in BIS to tracheal intubation during sevoflurane but not desflurane anesthesia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 214~217 | - |
dc.relation.isPartOf | JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adrenergic beta-Antagonists/therapeutic use* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anesthesia, Inhalation* | - |
dc.subject.MESH | Anesthetics, Inhalation* | - |
dc.subject.MESH | Blood Pressure/drug effects | - |
dc.subject.MESH | Double-Blind Method | - |
dc.subject.MESH | Electroencephalography/drug effects* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Rate/drug effects | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intubation, Intratracheal* | - |
dc.subject.MESH | Isoflurane/analogs & derivatives* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Methyl Ethers* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Propanolamines/therapeutic use* | - |
dc.subject.MESH | Young Adult | - |
dc.title | A single dose of esmolol blunts the increase in bispectral index to tracheal intubation during sevoflurane but not desflurane anesthesia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | Seung Ho Choi | - |
dc.contributor.googleauthor | Chang Seok Kim | - |
dc.contributor.googleauthor | Jong Hoon Kim | - |
dc.contributor.googleauthor | Bum Su Kim | - |
dc.contributor.googleauthor | Eun Mi Kim | - |
dc.contributor.googleauthor | Kyeong Tae Min | - |
dc.identifier.doi | 10.1097/ANA.0b013e3181a41e69 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01400 | - |
dc.contributor.localId | A00930 | - |
dc.contributor.localId | A04101 | - |
dc.relation.journalcode | J01639 | - |
dc.identifier.eissn | 1537-1921 | - |
dc.identifier.pmid | 19542998 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00008506-200907000-00005&LSLINK=80&D=ovft | - |
dc.subject.keyword | BIS | - |
dc.subject.keyword | desflurane | - |
dc.subject.keyword | esmolol | - |
dc.subject.keyword | intubation | - |
dc.subject.keyword | sevoflurane | - |
dc.contributor.alternativeName | Min, Kyeong Tae | - |
dc.contributor.alternativeName | Kim, Jong Hoon | - |
dc.contributor.alternativeName | Choi, Seung Ho | - |
dc.contributor.affiliatedAuthor | Min, Kyeong Tae | - |
dc.contributor.affiliatedAuthor | Kim, Jong Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Seung Ho | - |
dc.citation.volume | 21 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 214 | - |
dc.citation.endPage | 217 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY, Vol.21(3) : 214-217, 2009 | - |
dc.identifier.rimsid | 46759 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.