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In vitro derby imaging of cancer biomarkers using quantum dots

DC FieldValueLanguage
dc.contributor.author강원준-
dc.date.accessioned2015-04-24T16:41:06Z-
dc.date.available2015-04-24T16:41:06Z-
dc.date.issued2009-
dc.identifier.issn1613-6810-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/103978-
dc.description.abstractSemiconductor quantum dots (QDs), which have broad absorption with narrow emission spectra, are useful for multiplex imaging. Here, fluorescence derby imaging using dual color QDs conjugated by the AS1411 aptamer (targeting nucleolin) and the arginine-glycine-aspartic acid (targeting the integrin alpha(v)beta(3)) in cancer cells is reported. Simultaneous fluorescence imaging of cellular distribution of nucleolin and integrin alpha(v)beta(3) using QDs enables easy monitoring of separate targets in the cancer cells and the normal healthy cells. These results suggest the feasibility of a concurrent visualization of QD-based multiple cancer biomarkers using small molecules such as aptamer or peptide ligands.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1207~1212-
dc.relation.isPartOfSMALL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBiomarkers, Tumor/metabolism*-
dc.subject.MESHCell Line, Tumor-
dc.subject.MESHFluorescence-
dc.subject.MESHHumans-
dc.subject.MESHImaging, Three-Dimensional/methods*-
dc.subject.MESHIntegrin alphaVbeta3/metabolism-
dc.subject.MESHMicroscopy, Confocal-
dc.subject.MESHOligodeoxyribonucleotides/metabolism-
dc.subject.MESHOligopeptides/metabolism-
dc.subject.MESHPhosphoproteins/metabolism-
dc.subject.MESHQuantum Dots*-
dc.subject.MESHRNA-Binding Proteins/metabolism-
dc.titleIn vitro derby imaging of cancer biomarkers using quantum dots-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Nuclear Medicine (핵의학)-
dc.contributor.googleauthorMee Hyang Ko-
dc.contributor.googleauthorSoonhag Kim-
dc.contributor.googleauthorWon Jun Kang-
dc.contributor.googleauthorJung Hwan Lee-
dc.contributor.googleauthorHyungu Kang-
dc.contributor.googleauthorSung Hwan Moon-
dc.contributor.googleauthorDo Won Hwang-
dc.contributor.googleauthorHae Young Ko-
dc.contributor.googleauthorDong Soo Lee-
dc.identifier.doi10.1002/smll.200801580-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00062-
dc.relation.journalcodeJ02664-
dc.identifier.eissn1613-6829-
dc.identifier.pmid19235198-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/smll.200801580/abstract-
dc.contributor.alternativeNameKang, Won Jun-
dc.contributor.affiliatedAuthorKang, Won Jun-
dc.citation.volume5-
dc.citation.number10-
dc.citation.startPage1207-
dc.citation.endPage1212-
dc.identifier.bibliographicCitationSMALL, Vol.5(10) : 1207-1212, 2009-
dc.identifier.rimsid46739-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

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