Cited 9 times in
Circulating IL-8 levels in heart failure patients with and without metabolic syndrome
DC Field | Value | Language |
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dc.contributor.author | 강석민 | - |
dc.contributor.author | 이상학 | - |
dc.contributor.author | 정남식 | - |
dc.date.accessioned | 2015-04-24T16:39:02Z | - |
dc.date.available | 2015-04-24T16:39:02Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0009-8981 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103913 | - |
dc.description.abstract | BACKGROUND: It has been suggested that the metabolic syndrome (MetS) is associated with increased risk for heart failure (HF) and progression of HF. However, the underlying mechanisms are unclear. We tested whether the presence of the MetS would be associated with the increased degree of inflammatory state in HF. METHODS: Ninety-one eligible consecutive stable HF patients participated in this cross-sectional study. Anthropometric measurements were carried out and serum concentrations of lipoproteins, apolipoproteins (apoB, apoAI) and high sensitivity C-reactive protein (hsCRP) were measured. The simultaneous measurement of 17 cytokines using bioplex analysis was used. RESULT: Thirty-five subjects (39% of total, 48% of males and 31% of females) were classified as having the MetS in total HF patients. Serum concentrations of apoB (p<0.005) were significantly higher and the ratio of apoAI and apoB was significantly lower (p<0.01) in HF patients with MetS than those without MetS. Plasma levels of IL-8 (p<0.05) were significantly higher in HF patients with MetS than those without MetS. In addition, serum concentrations of hsCRP (p<0.005) were significantly higher in HF patients with MetS compared to those without MetS. CONCLUSIONS: The MetS in HF is associated with increased degree of inflammation, which provides information regarding the relationship between inflammation and HF with MetS. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 139~142 | - |
dc.relation.isPartOf | CLINICA CHIMICA ACTA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Blood Glucose/metabolism | - |
dc.subject.MESH | C-Reactive Protein/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Failure/blood* | - |
dc.subject.MESH | Heart Failure/complications* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Interleukin-8/blood* | - |
dc.subject.MESH | Lipoproteins/blood | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Metabolic Syndrome/blood* | - |
dc.subject.MESH | Metabolic Syndrome/complications* | - |
dc.subject.MESH | Middle Aged | - |
dc.title | Circulating IL-8 levels in heart failure patients with and without metabolic syndrome | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Min-Jeong Shin | - |
dc.contributor.googleauthor | Kyung Hye Lee | - |
dc.contributor.googleauthor | Ji Hyung Chung | - |
dc.contributor.googleauthor | Yoo Kyoung Park | - |
dc.contributor.googleauthor | Mi Kyung Choi | - |
dc.contributor.googleauthor | Jaewon Oh | - |
dc.contributor.googleauthor | Ji Won Choi | - |
dc.contributor.googleauthor | Sang-Hak Lee | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.identifier.doi | 10.1016/j.cca.2009.04.020 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00037 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A02833 | - |
dc.relation.journalcode | J00543 | - |
dc.identifier.eissn | 1873-3492 | - |
dc.identifier.pmid | 19410569 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0009898109002253 | - |
dc.subject.keyword | Heart failure | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | C-reactive protein | - |
dc.subject.keyword | Interleukin-8 | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.alternativeName | Lee, Sang Hak | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Lee, Snag Hak | - |
dc.citation.volume | 405 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 139 | - |
dc.citation.endPage | 142 | - |
dc.identifier.bibliographicCitation | CLINICA CHIMICA ACTA, Vol.405(1-2) : 139-142, 2009 | - |
dc.identifier.rimsid | 37879 | - |
dc.type.rims | ART | - |
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