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Concomitant isochromosome 17q and trisomy 14 in a patient with myelodysplastic syndrome in leukemic transformation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김진석 | - |
dc.contributor.author | 박태성 | - |
dc.contributor.author | 송재우 | - |
dc.contributor.author | 양우익 | - |
dc.contributor.author | 이종한 | - |
dc.contributor.author | 최종락 | - |
dc.date.accessioned | 2015-04-24T16:35:04Z | - |
dc.date.available | 2015-04-24T16:35:04Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0091-7370 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103788 | - |
dc.description.abstract | We describe a novel case of simultaneous karyotypic abnormalities of isochromosome 17q and trisomy 14 in a patient with myelodysplastic syndrome (MDS) in leukemic transformation. A 66-yr-old Korean man was admitted to Severance Hospital for evaluation of pancytopenia. On the basis of bone marrow studies at 3 different stages, he was diagnosed with MDS in leukemic transformation. Chromosome karyotyping repeatedly showed the same main clonal abnormalities, including isochromosome 17q and trisomy 14. Isochromosome 17q and trisomy 14 have each been reported as rare, nonrandom recurrent chromosomal abnormalities in patients with MDS showing a poor prognosis. To our knowledge, this is the first report of concurrent i(17)(q10) and trisomy 14 in a patient with MDS in leukemic transformation | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 176~181 | - |
dc.relation.isPartOf | ANNALS OF CLINICAL AND LABORATORY SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Cell Transformation, Neoplastic/genetics* | - |
dc.subject.MESH | Chromosome Mapping | - |
dc.subject.MESH | Chromosomes, Human, Pair 14* | - |
dc.subject.MESH | Chromosomes, Human, Pair 17 | - |
dc.subject.MESH | Fatal Outcome | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Isochromosomes/genetics* | - |
dc.subject.MESH | Leukemia/genetics* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Myelodysplastic Syndromes/genetics* | - |
dc.subject.MESH | Trisomy* | - |
dc.title | Concomitant isochromosome 17q and trisomy 14 in a patient with myelodysplastic syndrome in leukemic transformation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Tae Sung Park | - |
dc.contributor.googleauthor | Jaewoo Song | - |
dc.contributor.googleauthor | Jong-Han Lee | - |
dc.contributor.googleauthor | Jin Seok Kim | - |
dc.contributor.googleauthor | Woo Ick Yang | - |
dc.contributor.googleauthor | Jong Rak Choi | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01017 | - |
dc.contributor.localId | A01725 | - |
dc.contributor.localId | A02054 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A03151 | - |
dc.contributor.localId | A04182 | - |
dc.relation.journalcode | J00155 | - |
dc.identifier.eissn | 1550-8080 | - |
dc.identifier.pmid | 19429805 | - |
dc.identifier.url | http://www.annclinlabsci.org/content/39/2/176.long | - |
dc.subject.keyword | isochromosome 17q | - |
dc.subject.keyword | trisomy 1 | - |
dc.subject.keyword | 4 myelodysplastic syndrome | - |
dc.subject.keyword | leukemic transformation | - |
dc.contributor.alternativeName | Kim, Jin Seok | - |
dc.contributor.alternativeName | Park, Tae Sung | - |
dc.contributor.alternativeName | Song, Jae Woo | - |
dc.contributor.alternativeName | Yang, Woo Ick | - |
dc.contributor.alternativeName | Lee, Jong Han | - |
dc.contributor.alternativeName | Choi, Jong Rak | - |
dc.contributor.affiliatedAuthor | Kim, Jin Seok | - |
dc.contributor.affiliatedAuthor | Park, Tae Sung | - |
dc.contributor.affiliatedAuthor | Song, Jae Woo | - |
dc.contributor.affiliatedAuthor | Yang, Woo Ick | - |
dc.contributor.affiliatedAuthor | Lee, Jong Han | - |
dc.contributor.affiliatedAuthor | Choi, Jong Rak | - |
dc.citation.volume | 39 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 176 | - |
dc.citation.endPage | 181 | - |
dc.identifier.bibliographicCitation | ANNALS OF CLINICAL AND LABORATORY SCIENCE, Vol.39(2) : 176-181, 2009 | - |
dc.identifier.rimsid | 36693 | - |
dc.type.rims | ART | - |
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