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Operative safety and oncologic outcomes of anal sphincter-preserving surgery with mesorectal excision for rectal cancer: 931 consecutive patients treated at a single institution

DC FieldValueLanguage
dc.contributor.author이강영-
dc.contributor.author김남규-
dc.contributor.author김영완-
dc.contributor.author조장환-
dc.contributor.author민병소-
dc.contributor.author손승국-
dc.date.accessioned2015-04-24T16:31:59Z-
dc.date.available2015-04-24T16:31:59Z-
dc.date.issued2009-
dc.identifier.issn1068-9265-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/103690-
dc.description.abstractBACKGROUND: This study was designed to evaluate the operative safety and long-term oncologic outcomes of sphincter-preserving surgery based on sharp mesorectal excision for rectal cancer. METHODS: Between January 1989 and June 2004, 931 patients underwent sphincter-preserving surgery based on sharp mesorectal excision. The operative safety and oncologic outcomes were assessed for the periods of 1989-1996 (n = 208) and 1997-2004 (n = 723). Total mesorectal excision (TME)-based sphincter-preserving surgery was performed during the period of 1989-1996. A multidisciplinary team approach and tailored mesorectal excision, which is the differential removal of the mesorectum, were our standard treatment for patients with rectal cancer during the period of 1997-2004. RESULTS: The use of preoperative chemoradiation (P < 0.001), ultralow anterior resection with coloanal anastomosis (P = 0.01), diverting stoma (P = 0.001), and <2 cm of a distal resection margin (P = 0.01) were more common during the period of 1997-2004. There were no differences between the two periods with regard to perioperative complications (P = 0.2), such as anastomosis leakage (2.4% vs. 3.6%). Cancer-specific survival rates (79.1% vs. 79.6%, P = 0.7) and local recurrence (8.4% vs. 8.6%, P = 0.99) did not differ significantly for the two periods. CONCLUSIONS: Based on sharp mesorectal excision, operative safety and oncologic outcomes were not compromised by technical advances in sphincter-preserving surgery using tailored mesorectal excision and a shortened distal margin.-
dc.description.statementOfResponsibilityopen-
dc.format.extent900~909-
dc.relation.isPartOfANNALS OF SURGICAL ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenocarcinoma/surgery*-
dc.subject.MESHAdenocarcinoma/therapy-
dc.subject.MESHAnal Canal-
dc.subject.MESHChemotherapy, Adjuvant-
dc.subject.MESHColectomy/methods*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoadjuvant Therapy-
dc.subject.MESHRadiotherapy, Adjuvant-
dc.subject.MESHRectal Neoplasms/surgery*-
dc.subject.MESHRectal Neoplasms/therapy-
dc.subject.MESHTreatment Outcome-
dc.titleOperative safety and oncologic outcomes of anal sphincter-preserving surgery with mesorectal excision for rectal cancer: 931 consecutive patients treated at a single institution-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorNam-Kyu Kim-
dc.contributor.googleauthorYoung-Wan Kim-
dc.contributor.googleauthorByung-Soh Min-
dc.contributor.googleauthorKang-Young Lee-
dc.contributor.googleauthorSeung-Kook Sohn-
dc.contributor.googleauthorChang-Hwan Cho-
dc.identifier.doi10.1245/s10434-009-0340-9-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02640-
dc.contributor.localIdA00353-
dc.contributor.localIdA00720-
dc.contributor.localIdA03894-
dc.contributor.localIdA01402-
dc.contributor.localIdA01978-
dc.relation.journalcodeJ00179-
dc.identifier.eissn1534-4681-
dc.identifier.pmid19198951-
dc.identifier.urlhttp://link.springer.com/article/10.1245%2Fs10434-009-0340-9-
dc.contributor.alternativeNameLee, Kang Young-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.alternativeNameKim, Young Wan-
dc.contributor.alternativeNameCho, Chang Hwan-
dc.contributor.alternativeNameMin, Byung Soh-
dc.contributor.alternativeNameSohn, Seung Kook-
dc.contributor.affiliatedAuthorLee, Kang Young-
dc.contributor.affiliatedAuthorKim, Nam Kyu-
dc.contributor.affiliatedAuthorKim, Young Wan-
dc.contributor.affiliatedAuthorCho, Chang Hwan-
dc.contributor.affiliatedAuthorMin, Byung Soh-
dc.contributor.affiliatedAuthorSohn, Seung Kook-
dc.citation.volume16-
dc.citation.number4-
dc.citation.startPage900-
dc.citation.endPage909-
dc.identifier.bibliographicCitationANNALS OF SURGICAL ONCOLOGY, Vol.16(4) : 900-909, 2009-
dc.identifier.rimsid36630-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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