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Therapy-related myelodysplastic syndrome/acute myeloid leukemia after treatment with temozolomide in a patient with glioblastoma multiforme.
DC Field | Value | Language |
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dc.contributor.author | 김세훈 | - |
dc.contributor.author | 송재우 | - |
dc.contributor.author | 이승태 | - |
dc.contributor.author | 최종락 | - |
dc.date.accessioned | 2015-04-24T16:31:20Z | - |
dc.date.available | 2015-04-24T16:31:20Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0091-7370 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103670 | - |
dc.description.abstract | Therapy-related myelodysplastic syndrome and acute leukemia after treatment with temozolomide have rarely been described in the literature. Only 10 cases in association with temozolomide have been documented. The cases included anaplastic astrocytoma (4 cases), anaplastic oligodendroglioma (2 cases), low grade astrocytoma (2 cases), low grade oligodendroglioma (1 case), and one case of secondary Philadelphia-positive acute lymphoblastic leukemia in a patient with glioblastoma multiforme. Here we report a novel case of therapy-related myelodysplastic syndrome/acute myeloid leukemia associated with der(1;7)(q10;p10) in a glioblastoma multiforme patient treated with temozolomide. Results of bone marrow morphology, chromosome, and fluorescent in situ hybridization (FISH) analyses, as well as the clinical history, strongly suggest a treatment-related etiology in our case. In past reports, karyotypes in cases of therapy-related myelodysplastic syndrome/acute myeloid leukemia mostly demonstrated abnormalities in chromosomes 5 and 7. However, we report a case of temozolomide-related myelodysplastic syndrome/acute myeloid leukemia with der(1;7)(q10;p10), possibly the first reported case, to the authors' knowledge. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 392~398 | - |
dc.relation.isPartOf | ANNALS OF CLINICAL AND LABORATORY SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Biopsy | - |
dc.subject.MESH | Bone Marrow Cells/pathology | - |
dc.subject.MESH | Brain Neoplasms/drug therapy | - |
dc.subject.MESH | Brain Neoplasms/pathology | - |
dc.subject.MESH | Dacarbazine/adverse effects | - |
dc.subject.MESH | Dacarbazine/analogs & derivatives* | - |
dc.subject.MESH | Dacarbazine/therapeutic use | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glioblastoma/drug therapy* | - |
dc.subject.MESH | Glioblastoma/pathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | In Situ Hybridization, Fluorescence | - |
dc.subject.MESH | Karyotyping | - |
dc.subject.MESH | Leukemia, Myeloid, Acute/chemically induced* | - |
dc.subject.MESH | Leukemia, Myeloid, Acute/complications | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myelodysplastic Syndromes/chemically induced* | - |
dc.subject.MESH | Myelodysplastic Syndromes/complications | - |
dc.subject.MESH | Skin/pathology | - |
dc.title | Therapy-related myelodysplastic syndrome/acute myeloid leukemia after treatment with temozolomide in a patient with glioblastoma multiforme. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Sue Jung Kim | - |
dc.contributor.googleauthor | Tae Sung Park | - |
dc.contributor.googleauthor | Seung Tae Lee | - |
dc.contributor.googleauthor | Jaewoo Song | - |
dc.contributor.googleauthor | Borum Suh | - |
dc.contributor.googleauthor | Se Hoon Kim | - |
dc.contributor.googleauthor | Seon Jung Jang | - |
dc.contributor.googleauthor | Chang Hoon Lee | - |
dc.contributor.googleauthor | Jong Rak Choi | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00610 | - |
dc.contributor.localId | A02054 | - |
dc.contributor.localId | A02930 | - |
dc.contributor.localId | A04182 | - |
dc.relation.journalcode | J00155 | - |
dc.identifier.eissn | 1550-8080 | - |
dc.identifier.pmid | 19880768 | - |
dc.identifier.url | http://www.annclinlabsci.org/content/39/4/392.long | - |
dc.contributor.alternativeName | Kim, Se Hoon | - |
dc.contributor.alternativeName | Song, Jae Woo | - |
dc.contributor.alternativeName | Lee, Seung Tae | - |
dc.contributor.alternativeName | Choi, Jong Rak | - |
dc.contributor.affiliatedAuthor | Kim, Se Hoon | - |
dc.contributor.affiliatedAuthor | Song, Jae Woo | - |
dc.contributor.affiliatedAuthor | Lee, Seung Tae | - |
dc.contributor.affiliatedAuthor | Choi, Jong Rak | - |
dc.citation.volume | 39 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 392 | - |
dc.citation.endPage | 398 | - |
dc.identifier.bibliographicCitation | ANNALS OF CLINICAL AND LABORATORY SCIENCE, Vol.39(4) : 392-398, 2009 | - |
dc.identifier.rimsid | 36614 | - |
dc.type.rims | ART | - |
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