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Quality of life for Korean patients with vitiligo: Skindex-29 and its correlation with clinical profiles

 Do Young KIM  ;  Jae Won LEE  ;  Se Hee WHANG  ;  Yoon Kee PARK  ;  Seung-Kyung HANN  ;  Yee Jin SHIN 
 JOURNAL OF DERMATOLOGY, Vol.36(6) : 317-322, 2009 
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Issue Date
Adult ; Aged ; Asian Continental Ancestry Group ; Female ; Humans ; Korea ; Male ; Middle Aged ; Quality of Life* ; Severity of Illness Index ; Vitiligo/psychology* ; Young Adult
clinical profiles ; quality of life ; Skindex-29 ; vitiligo
Vitiligo considerably influences the psychological well-being of patients. Disease-induced disfigurement can cause patients to experience a high level of stigmatization, which can lead to psychosocial stresses and negative impacts on quality of life (QOL). This study aims to ascertain the QOL of vitiligo patients compared to patients with other mild skin disorders. We also attempt to study which clinical features of vitiligo are closely related to the patient's QOL. One hundred and thirty-three vitiligo patients and 112 patients with mild skin disorders were analyzed. All participants were asked to fill out questionnaires covering comprehensive clinical profiles and the Korean version of Skindex-29. Statistical correlation between Skindex-29 and each clinical profile were analyzed. The symptom scale of Skindex-29 was significantly lower in vitiligo patients than in controls, but the function scale and the emotion scale were significantly higher in the vitiligo group than in controls. However, the difference in function scales between groups was significant in female patients, but not in male patients. Several clinical profiles, such as duration of disease, severity scores and previous history of treatments, showed close correlations with the function scale. Family history of vitiligo, Köebner phenomenon, patients' perspectives on disease prognosis, and discordance of the severity scores between physicians and patients also influenced the Skindex-29 subscales differently. In conclusion, the present study suggests that patients with vitiligo were highly affected in the functional and emotional aspects of QOL, with some sex differences. Various clinical features may play an important role in the QOL of vitiligo patients
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1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Young(김도영) ORCID logo https://orcid.org/0000-0002-0194-9854
Park, Yoon Kee(박윤기)
Shin, Yee Jin(신의진) ORCID logo https://orcid.org/0000-0001-8573-4342
Hann, Seung Kyung(한승경)
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