Cited 43 times in
Vancomycin-resistant enterococci bacteremia: risk factors for mortality and influence of antimicrobial therapy on clinical outcome
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김준명 | - |
dc.contributor.author | 김창오 | - |
dc.contributor.author | 송영구 | - |
dc.contributor.author | 용동은 | - |
dc.contributor.author | 이경원 | - |
dc.contributor.author | 이한성 | - |
dc.contributor.author | 정수진 | - |
dc.contributor.author | 진범식 | - |
dc.contributor.author | 최준용 | - |
dc.contributor.author | 최희경 | - |
dc.contributor.author | 한상훈 | - |
dc.date.accessioned | 2015-04-24T16:27:32Z | - |
dc.date.available | 2015-04-24T16:27:32Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0163-4453 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103550 | - |
dc.description.abstract | OBJECTIVES: This study evaluated the effects of antimicrobial treatment against vancomycin-resistant enterococci (VRE) and delayed administration of anti-VRE therapy on mortality, and determined independent risk factors for delayed all-cause mortality of VRE bacteremia patients. METHODS: Over 10 years, 153 patients with clinically significant monomicrobial VRE bacteremia were identified among a total of 2834 patients in a VRE cohort. The main outcomes were immediate (7-day) and delayed (28-day, 60-day) all-cause mortality. RESULTS: The 7-day (P<0.001) and 28-day (P=0.041) mortalities were lower in the group receiving anti-VRE therapy, but the 60-day mortality (P=0.113) was unaffected. The mortalities of patients receiving anti-VRE therapy later than 72h after the onset of bacteremia were no different from that of patients receiving treatment within 72h. Both a higher APACHE II score (hazard ratio [HR], 1.10; P<0.001 and HR, 1.12; P<0.001, respectively) and the presence of septic shock at the onset of bacteremia (HR, 1.91; P=0.047 and HR, 1.78; P=0.034, respectively) were independent risk factors for 28-day and 60-day mortality. CONCLUSION: These findings suggest that in spite of antibiotic therapy against VRE, patients with VRE bacteremia eventually have a higher risk of death because of severe illness at the onset of bacteremia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 182~190 | - |
dc.relation.isPartOf | JOURNAL OF INFECTION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | APACHE | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anti-Bacterial Agents/therapeutic use* | - |
dc.subject.MESH | Bacteremia/drug therapy* | - |
dc.subject.MESH | Bacteremia/microbiology* | - |
dc.subject.MESH | Bacteremia/mortality | - |
dc.subject.MESH | Enterococcus/drug effects* | - |
dc.subject.MESH | Enterococcus/isolation & purification | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/drug therapy* | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/microbiology* | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/mortality | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Shock, Septic | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Vancomycin Resistance* | - |
dc.title | Vancomycin-resistant enterococci bacteremia: risk factors for mortality and influence of antimicrobial therapy on clinical outcome | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Sang Hoon Han | - |
dc.contributor.googleauthor | Bum Sik Chin | - |
dc.contributor.googleauthor | Han Sung Lee | - |
dc.contributor.googleauthor | Su Jin Jeong | - |
dc.contributor.googleauthor | Hee Kyoung Choi | - |
dc.contributor.googleauthor | Chang Oh Kim | - |
dc.contributor.googleauthor | Dongeun Yong | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Young Goo Song | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.identifier.doi | 10.1016/j.jinf.2009.01.013 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A01044 | - |
dc.contributor.localId | A02037 | - |
dc.contributor.localId | A02423 | - |
dc.contributor.localId | A02649 | - |
dc.contributor.localId | A03277 | - |
dc.contributor.localId | A03638 | - |
dc.contributor.localId | A03981 | - |
dc.contributor.localId | A04191 | - |
dc.contributor.localId | A04228 | - |
dc.contributor.localId | A04286 | - |
dc.relation.journalcode | J01452 | - |
dc.identifier.eissn | 1532-2742 | - |
dc.identifier.pmid | 19233476 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S016344530900036X | - |
dc.subject.keyword | Vancomycin-resistant enterococci | - |
dc.subject.keyword | Bacteremia | - |
dc.subject.keyword | Mortality | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Kim, Chang Oh | - |
dc.contributor.alternativeName | Song, Young Goo | - |
dc.contributor.alternativeName | Yong, Dong Eun | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.alternativeName | Lee, Han Sung | - |
dc.contributor.alternativeName | Jeong, Su Jin | - |
dc.contributor.alternativeName | Chin, Bum Sik | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.alternativeName | Choi, Hee Kyoung | - |
dc.contributor.alternativeName | Han, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Kim, Chang Oh | - |
dc.contributor.affiliatedAuthor | Song, Young Goo | - |
dc.contributor.affiliatedAuthor | Yong, Dong Eun | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Lee, Han Sung | - |
dc.contributor.affiliatedAuthor | Jeong, Su Jin | - |
dc.contributor.affiliatedAuthor | Chin, Bum Sik | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Choi, Hee Kyoung | - |
dc.contributor.affiliatedAuthor | Han, Sang Hoon | - |
dc.citation.volume | 58 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 182 | - |
dc.citation.endPage | 190 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INFECTION, Vol.58(3) : 182-190, 2009 | - |
dc.identifier.rimsid | 37919 | - |
dc.type.rims | ART | - |
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