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발기부전 환자에서 홍삼농축분말의 유효성 및 안전성: 다기관, 무작위배정, 이중맹검, 위약 대조 임상연구

Other Titles
 Efficacy and Safety of Red Ginseng Extract Powder in Patients with Erectile Dysfunction: Multicenter, Randomized, Double-Blind, Placebo-Controlled Study 
Authors
 함원식  ;  김원태  ;  이진선  ;  주희정  ;  강신정  ;  오진환  ;  허 율  ;  정재용  ;  박광성  ;  최영득 
Citation
 KOREAN JOURNAL OF UROLOGY, Vol.50(2) : 159-164, 2009 
Journal Title
 KOREAN JOURNAL OF UROLOGY 
ISSN
 2005-6737 
Issue Date
2009
Keywords
Ginseng ; Erectile dysfunction ; Treatment efficacy
Abstract
PURPOSE: To evaluate the safety and efficacy of red ginseng extract powder (OKBT) for treating erectile dysfunction. MATERIALS AND METHODS: Sixty-nine adult patients with mild to moderate erectile dysfunction of various etiologies were randomized to receive placebo or red ginseng extract powder. The red ginseng extract powder used in the present study was named OKBT. The primary efficacy parameter was response to the International Index of Erectile Function (IIEF) erectile function domain at baseline and week 8. Other IIEF domain scores were evaluated as secondary parameters. For safety evaluation, we performed history taking, physical examination, clinical laboratory tests, and hormonal tests at baseline and week 8. RESULTS: There were no significant differences in the patients' characteristics between the 2 groups. After 8 weeks of administration, primary efficacy (erectile function domain) and all secondary efficacy domains were significantly improved in the OKBT group compared with the placebo group (p<0.05). Notably, even the domain related to sexual desire, frequency and degree of sexual desire, was also improved in the OKBT group (p<0.001). There were no significant adverse reactions with OKBT administration, and there were also no significant differences in the results of laboratory tests between the 2 groups after administration. CONCLUSIONS: Our data show that red ginseng extract powder can be used as an alternative remedy for Korean men suffering from mild to moderate erectile dysfunction
Files in This Item:
T200900569.pdf Download
DOI
10.4111/kju.2009.50.2.159
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Won Tae(김원태)
Ju, Hee Jeong(주희정)
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
Ham, Won Sik(함원식) ORCID logo https://orcid.org/0000-0003-2246-8838
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/103514
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