Cited 29 times in
Invasive pulmonary aspergillosis after solid organ transplantation: diagnosis and treatment based on 28 years of transplantation experience
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김명수 | - |
dc.contributor.author | 김수진 | - |
dc.contributor.author | 김순일 | - |
dc.contributor.author | 김유선 | - |
dc.contributor.author | 장혜경 | - |
dc.contributor.author | 주동진 | - |
dc.contributor.author | 주만기 | - |
dc.date.accessioned | 2015-04-24T16:25:44Z | - |
dc.date.available | 2015-04-24T16:25:44Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0041-1345 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103495 | - |
dc.description.abstract | Invasive pulmonary aspergillosis (IPA) is a serious and lethal complication among organ transplant recipients. This report described the clinical manifestations and treatment of IPA over a 28-year period. From January 1979 to December 2007, 3215 organ transplant patients (2954 kidney and 261 liver recipients) were enrolled in the study. Nine patients developed IPA (7 kidney and 2 liver recipients), yielding an incidence of 0.003% (9/3215). Five IPA patients (55.6%) were diagnosed by transbronchial lung biopsy or autopsy, and 3 (33.3%) by sputum culture study. One patient was diagnosed through clinical manifestations and observations of IPA characteristics on chest X ray. We used amphotericin B (n = 4; 44.4%), voriconazole (n = 2; 22.2%), or fluconazole (n = 1; 11.1%) as the primary antifungal agents, but 2 patients could not receive antifungal agents due to rapid disease progression and sequential mortality. This study showed a high mortality rate among IPA patients (55.6%; 5/9). Only patients who received early antifungal agent thereby after a prompt diagnosis recovered from IPA. This survival advantage warrants careful monitoring for invasive fungal infections after organ transplantation with immediate administration of antifungal agents or surgical intervention. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 375~378 | - |
dc.relation.isPartOf | TRANSPLANTATION PROCEEDINGS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Antifungal Agents/therapeutic use* | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Drug Therapy, Combination | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunosuppressive Agents/therapeutic use | - |
dc.subject.MESH | Kidney Transplantation/adverse effects* | - |
dc.subject.MESH | Liver Transplantation/adverse effects* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Postoperative Complications/immunology | - |
dc.subject.MESH | Postoperative Complications/microbiology* | - |
dc.subject.MESH | Postoperative Complications/mortality | - |
dc.subject.MESH | Pulmonary Aspergillosis/diagnosis* | - |
dc.subject.MESH | Pulmonary Aspergillosis/diagnostic imaging | - |
dc.subject.MESH | Pulmonary Aspergillosis/epidemiology* | - |
dc.subject.MESH | Pulmonary Aspergillosis/mortality | - |
dc.subject.MESH | Radiography, Thoracic | - |
dc.subject.MESH | Reoperation/statistics & numerical data | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Survivors | - |
dc.title | Invasive pulmonary aspergillosis after solid organ transplantation: diagnosis and treatment based on 28 years of transplantation experience | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | M.K. Ju | - |
dc.contributor.googleauthor | D.J. Joo | - |
dc.contributor.googleauthor | S.J. Kim | - |
dc.contributor.googleauthor | H.K. Chang | - |
dc.contributor.googleauthor | M.S. Kim | - |
dc.contributor.googleauthor | S.I. Kim | - |
dc.contributor.googleauthor | Y.S. Kim | - |
dc.identifier.doi | 10.1016/j.transproceed.2008.11.006 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00636 | - |
dc.contributor.localId | A00649 | - |
dc.contributor.localId | A00785 | - |
dc.contributor.localId | A03494 | - |
dc.contributor.localId | A03948 | - |
dc.contributor.localId | A03949 | - |
dc.contributor.localId | A00424 | - |
dc.relation.journalcode | J02755 | - |
dc.identifier.eissn | 1873-2623 | - |
dc.identifier.pmid | 19249560 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0041134508016023 | - |
dc.contributor.alternativeName | Kim, Myoung Soo | - |
dc.contributor.alternativeName | Kim, Soo Jin | - |
dc.contributor.alternativeName | Kim, Soon Il | - |
dc.contributor.alternativeName | Kim, Yu Seun | - |
dc.contributor.alternativeName | Chang, Hye Kyung | - |
dc.contributor.alternativeName | Joo, Dong Jin | - |
dc.contributor.alternativeName | Joo, Man Ki | - |
dc.contributor.affiliatedAuthor | Kim, Soo Jin | - |
dc.contributor.affiliatedAuthor | Kim, Soon Il | - |
dc.contributor.affiliatedAuthor | Kim, Yu Seun | - |
dc.contributor.affiliatedAuthor | Chang, Hye Kyung | - |
dc.contributor.affiliatedAuthor | Joo, Dong Jin | - |
dc.contributor.affiliatedAuthor | Joo, Man Ki | - |
dc.contributor.affiliatedAuthor | Kim, Myoung Soo | - |
dc.citation.volume | 41 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 375 | - |
dc.citation.endPage | 378 | - |
dc.identifier.bibliographicCitation | TRANSPLANTATION PROCEEDINGS, Vol.41(1) : 375-378, 2009 | - |
dc.identifier.rimsid | 36041 | - |
dc.type.rims | ART | - |
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