Cited 16 times in
Elevated cardiac troponin T predicts cardiovascular events in asymptomatic continuous ambulatory peritoneal dialysis patients without a history of cardiovascular disease
DC Field | Value | Language |
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dc.contributor.author | 김동기 | - |
dc.contributor.author | 김범석 | - |
dc.contributor.author | 문성진 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 이정은 | - |
dc.contributor.author | 이호영 | - |
dc.contributor.author | 최규헌 | - |
dc.contributor.author | 최훈영 | - |
dc.contributor.author | 한대석 | - |
dc.contributor.author | 한승진 | - |
dc.contributor.author | 강신욱 | - |
dc.date.accessioned | 2015-04-24T16:23:00Z | - |
dc.date.available | 2015-04-24T16:23:00Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0250-8095 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103413 | - |
dc.description.abstract | BACKGROUND: Recent studies revealed that elevated cardiac troponin T (cTnT) could predict all-cause mortality and cardiovascular diseases in end-stage renal disease patients. This study aimed to evaluate cTnT as a prognostic value in asymptomatic continuous ambulatory peritoneal dialysis patients. METHODS: This is a prospective observational study with 107 prevalent peritoneal dialysis patients. cTnT, high-sensitive C-reactive protein (hsCRP) and IL-6 were measured at baseline. Based on cTnT level, patients were classified as higher cTnT group (HT, n = 21, cTnT > or =0.1 ng/ml) and lower cTnT group (LT, n = 86, cTnT <0.1 ng/ml), and were followed for 3 years. Primary endpoint was cardiovascular events. RESULTS: The HT group had a significantly higher level of log hsCRP and log IL-6 than the LT group (p < 0.05). Kaplan-Meier survival demonstrated worse cardiovascular event-free survival for the HT group. Multivariate analysis adjusted for age, cTnT, IL-6 and hsCRP level revealed that age (per 1-year increase, HR 1.07, p < 0.05), elevated cTnT (vs. <0.1 ng/ml, HR 5.89, p < 0.05) and hsCRP (vs. <3.0 mg/l, HR 4.15, p < 0.05) were identified as significant determinants of cardiovascular events. CONCLUSION: This study suggests that cTnT may be an aid in risk stratification of continuous ambulatory peritoneal dialysis patients | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 129~135 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF NEPHROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | C-Reactive Protein/metabolism | - |
dc.subject.MESH | Cardiovascular Diseases/blood* | - |
dc.subject.MESH | Cardiovascular Diseases/mortality* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Interleukin-6/blood | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Kidney Failure, Chronic/blood* | - |
dc.subject.MESH | Kidney Failure, Chronic/mortality* | - |
dc.subject.MESH | Kidney Failure, Chronic/therapy | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Peritoneal Dialysis, Continuous Ambulatory/statistics & numerical data* | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Troponin T/blood* | - |
dc.title | Elevated cardiac troponin T predicts cardiovascular events in asymptomatic continuous ambulatory peritoneal dialysis patients without a history of cardiovascular disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.contributor.googleauthor | Hoon Young Choi | - |
dc.contributor.googleauthor | Dong Ki Kim | - |
dc.contributor.googleauthor | Sung Jin Moon | - |
dc.contributor.googleauthor | Jung Eun Lee | - |
dc.contributor.googleauthor | Tae Hyun Yoo | - |
dc.contributor.googleauthor | Beom Seok Kim | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Kyu Hun Choi | - |
dc.contributor.googleauthor | Ho Yung Lee | - |
dc.contributor.googleauthor | Dae-Suk Han | - |
dc.identifier.doi | 10.1159/000151634 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00488 | - |
dc.contributor.localId | A01364 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A03326 | - |
dc.contributor.localId | A04043 | - |
dc.contributor.localId | A04226 | - |
dc.contributor.localId | A04272 | - |
dc.contributor.localId | A04302 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A03119 | - |
dc.contributor.localId | A00400 | - |
dc.relation.journalcode | J00094 | - |
dc.identifier.eissn | 1421-9670 | - |
dc.identifier.pmid | 18719346 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/151634 | - |
dc.subject.keyword | Cardiac troponin T | - |
dc.subject.keyword | Peritoneal dialysis | - |
dc.subject.keyword | Cardiovascular events | - |
dc.contributor.alternativeName | Kim, Dong Ki | - |
dc.contributor.alternativeName | Kim, Beom Seok | - |
dc.contributor.alternativeName | Moon, Sung Jin | - |
dc.contributor.alternativeName | Yoo, Tae Hyun | - |
dc.contributor.alternativeName | Lee, Jung Eun | - |
dc.contributor.alternativeName | Lee, Ho Yung | - |
dc.contributor.alternativeName | Choi, Kyu Hun | - |
dc.contributor.alternativeName | Choi, Hoon Young | - |
dc.contributor.alternativeName | Han, Dae Suk | - |
dc.contributor.alternativeName | Han, Seung Jin | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | Kim, Beom Seok | - |
dc.contributor.affiliatedAuthor | Moon, Sung Jin | - |
dc.contributor.affiliatedAuthor | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Ho Yung | - |
dc.contributor.affiliatedAuthor | Choi, Kyu Hun | - |
dc.contributor.affiliatedAuthor | Choi, Hoon Young | - |
dc.contributor.affiliatedAuthor | Han, Dae Suk | - |
dc.contributor.affiliatedAuthor | Han, Seung Jin | - |
dc.contributor.affiliatedAuthor | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | Lee, Jung Eun | - |
dc.contributor.affiliatedAuthor | Kim, Dong Ki | - |
dc.citation.volume | 29 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 129 | - |
dc.citation.endPage | 135 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF NEPHROLOGY, Vol.29(2) : 129-135, 2009 | - |
dc.identifier.rimsid | 37324 | - |
dc.type.rims | ART | - |
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