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Prognostic factors affecting oncologic outcomes in patients with locally recurrent rectal cancer: impact of patterns of pelvic recurrence on curative resection

DC FieldValueLanguage
dc.contributor.author김영완-
dc.contributor.author김영태-
dc.contributor.author노재경-
dc.contributor.author민병소-
dc.contributor.author성진실-
dc.contributor.author손승국-
dc.contributor.author최영득-
dc.contributor.author금기창-
dc.contributor.author허혁-
dc.contributor.author김남규-
dc.date.accessioned2015-04-24T16:21:39Z-
dc.date.available2015-04-24T16:21:39Z-
dc.date.issued2009-
dc.identifier.issn1435-2443-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/103383-
dc.description.abstractBACKGROUND: The purpose of this study is to investigate prognostic factors affecting oncologic outcomes in patients with locally recurrent rectal cancer and determine whether recurrence patterns influence curative resection of recurrent tumor. MATERIALS AND METHODS: We examined 62 patients with isolated local recurrence following total mesorectal excision (TME) of the primary rectal cancer. Recurrence patterns were classified as central, anterior, posterior, lateral, and perineal with respect to the intra-pelvic tumor location. Prognostic factors affecting oncologic outcomes were analyzed, and the rate of curative resection was analyzed according to recurrence patterns. RESULTS: The mean follow-up period was 49.0 +/- 29.0 months, and the mean time to recurrence after TME was 27.9 +/- 23.3 months. Twenty-three patients underwent curative resection, and the remaining 39 patients received palliative treatment. Patients with a central recurrence had the highest rate of curative resection (p = 0.006). The overall 5-year survival rate was 13.9% and significantly higher in those treated with curative resection (35.1%; p = 0.0002). Multivariate analysis demonstrated that disease-free survival less than 1 year and curative resection of local recurrence were independent prognostic factors influencing 5-year survival. CONCLUSION: Patients with central recurrences have a high probability of curative resection. Disease-free survival less than 1 year and curative resection of local recurrence were independent prognostic factors affecting oncologic outcomes in patients with locally recurrent rectal cancer-
dc.description.statementOfResponsibilityopen-
dc.format.extent71~77-
dc.relation.isPartOfLANGENBECKS ARCHIVES OF SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHNeoadjuvant Therapy-
dc.subject.MESHNeoplasm Recurrence, Local/drug therapy-
dc.subject.MESHNeoplasm Recurrence, Local/mortality-
dc.subject.MESHNeoplasm Recurrence, Local/radiotherapy-
dc.subject.MESHNeoplasm Recurrence, Local/surgery*-
dc.subject.MESHPalliative Care-
dc.subject.MESHPelvic Exenteration-
dc.subject.MESHPelvic Neoplasms/mortality-
dc.subject.MESHPelvic Neoplasms/secondary*-
dc.subject.MESHPelvic Neoplasms/surgery-
dc.subject.MESHPrognosis-
dc.subject.MESHRectal Neoplasms/drug therapy-
dc.subject.MESHRectal Neoplasms/mortality-
dc.subject.MESHRectal Neoplasms/radiotherapy-
dc.subject.MESHRectal Neoplasms/surgery*-
dc.subject.MESHReoperation-
dc.subject.MESHSacrum/surgery-
dc.titlePrognostic factors affecting oncologic outcomes in patients with locally recurrent rectal cancer: impact of patterns of pelvic recurrence on curative resection-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJea-Kun Park-
dc.contributor.googleauthorYoung-Wan Kim-
dc.contributor.googleauthorHyuk Hur-
dc.contributor.googleauthorNam-Kyu Kim-
dc.contributor.googleauthorByung-Soh Min-
dc.contributor.googleauthorSeung-Kook Sohn-
dc.contributor.googleauthorYoung-Deuk Choi-
dc.contributor.googleauthorYoung-Tae Kim-
dc.contributor.googleauthorJung-Bai Ahn-
dc.contributor.googleauthorJae-Kyung Roh-
dc.contributor.googleauthorKi-Chang Keum-
dc.contributor.googleauthorJin-Sil Seong-
dc.identifier.doi10.1007/s00423-008-0391-6-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00720-
dc.contributor.localIdA00729-
dc.contributor.localIdA01290-
dc.contributor.localIdA01402-
dc.contributor.localIdA01956-
dc.contributor.localIdA01978-
dc.contributor.localIdA04111-
dc.contributor.localIdA00272-
dc.contributor.localIdA04373-
dc.contributor.localIdA00353-
dc.relation.journalcodeJ03195-
dc.identifier.eissn1435-2451-
dc.identifier.pmid18663464-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00423-008-0391-6-
dc.subject.keywordRectal neoplasm-
dc.subject.keywordLocal recurrence-
dc.subject.keywordRecurrence pattern-
dc.subject.keywordCurative resection-
dc.subject.keywordSurvival-
dc.contributor.alternativeNameKim, Young Wan-
dc.contributor.alternativeNameKim, Young Tae-
dc.contributor.alternativeNameRoh, Jae Kyung-
dc.contributor.alternativeNameMin, Byung Soh-
dc.contributor.alternativeNameSeong, Jin Sil-
dc.contributor.alternativeNameSohn, Seung Kook-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.alternativeNameKeum, Ki Chang-
dc.contributor.alternativeNameHur, Hyuk-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.affiliatedAuthorKim, Young Wan-
dc.contributor.affiliatedAuthorKim, Young Tae-
dc.contributor.affiliatedAuthorRoh, Jae Kyung-
dc.contributor.affiliatedAuthorMin, Byung Soh-
dc.contributor.affiliatedAuthorSeong, Jin Sil-
dc.contributor.affiliatedAuthorSohn, Seung Kook-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.contributor.affiliatedAuthorKeum, Ki Chang-
dc.contributor.affiliatedAuthorHur, Hyuk-
dc.contributor.affiliatedAuthorKim, Nam Kyu-
dc.citation.volume394-
dc.citation.number1-
dc.citation.startPage71-
dc.citation.endPage77-
dc.identifier.bibliographicCitationLANGENBECKS ARCHIVES OF SURGERY, Vol.394(1) : 71-77, 2009-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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