2 386

Cited 41 times in

Plasma adiponectin and resistin levels as predictors of mortality in patients with acute myocardial infarction: data from infarction prognosis study registry

DC FieldValueLanguage
dc.contributor.author장양수-
dc.contributor.author정남식-
dc.contributor.author최동훈-
dc.contributor.author최의영-
dc.contributor.author하종원-
dc.contributor.author강석민-
dc.contributor.author김중선-
dc.contributor.author박성하-
dc.contributor.author이상학-
dc.date.accessioned2015-04-24T16:21:35Z-
dc.date.available2015-04-24T16:21:35Z-
dc.date.issued2009-
dc.identifier.issn0954-6928-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/103381-
dc.description.abstractBACKGROUND: Adiponectin and resistin, which have counteracting effects, are suggested to be associated with inflammation and atherosclerosis. The relationship between their levels and prognosis in high risk patients is, however, still unclear. The aim of this study was to evaluate the prognostic values of these adipokines in patients with acute myocardial infarction (MI). METHODS: Adiponectin and resistin levels were measured at acute phase of MI in 397 consecutive patients. All patients were followed-up for the occurrence of all-cause and cardiovascular mortalities. Predictors for all-cause and cardiovascular mortalities were analyzed by Cox proportional hazard model. RESULTS: During the mean follow-up period of 12 months, 28 (7.1%) patients died. Unadjusted all-cause mortality rate was significantly higher in patients with high tertiles of adiponectin (P=0.002) and resistin (P=0.002) levels. After controlling of clinical and laboratory variables, age [95% confidence interval (CI): 1.20-2.83, P=0.006], adiponectin (95% CI: 1.01-1.22, P=0.040), resistin (95% CI: 1.06-2.33, P=0.025), and statin use (95% CI: 0.15-0.83, P=0.017) were found to be independent predictors of all-cause mortality. For cardiovascular mortality, only age (95% CI: 1.33-3.25, P=0.001) and renal insufficiency (95% CI: 1.52-12.22, P=0.006) were independent predictors. CONCLUSION: High plasma adiponectin and resistin levels were predictors for all-cause mortality independent of other risk factors in patients with acute MI. These results confirmed and extended the positive correlations between these adipokines and mortality to a population consisting exclusively of MI.-
dc.description.statementOfResponsibilityopen-
dc.format.extent33~39-
dc.relation.isPartOfCORONARY ARTERY DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdiponectin/blood-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction/blood*-
dc.subject.MESHMyocardial Infarction/mortality*-
dc.subject.MESHMyocardial Infarction/therapy-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPrognosis-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHProspective Studies-
dc.subject.MESHRegistries-
dc.subject.MESHResistin/blood*-
dc.subject.MESHRisk Assessment-
dc.subject.MESHRisk Factors-
dc.subject.MESHTime Factors-
dc.subject.MESHUp-Regulation-
dc.titlePlasma adiponectin and resistin levels as predictors of mortality in patients with acute myocardial infarction: data from infarction prognosis study registry-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSang-Hak Lee-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorEui-Young Choi-
dc.contributor.googleauthorSungha Park-
dc.contributor.googleauthorSeok-Min Kang-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.1097/MCA.0b013e328318ecb0-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03448-
dc.contributor.localIdA03585-
dc.contributor.localIdA04053-
dc.contributor.localIdA04165-
dc.contributor.localIdA04257-
dc.contributor.localIdA00037-
dc.contributor.localIdA00961-
dc.contributor.localIdA01512-
dc.contributor.localIdA02833-
dc.relation.journalcodeJ00649-
dc.identifier.eissn1473-5830-
dc.identifier.pmid18997620-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00019501-200901000-00006&LSLINK=80&D=ovft-
dc.subject.keywordadiponectin-
dc.subject.keyworddeath-
dc.subject.keywordmyocardial infarction-
dc.subject.keywordresistin-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameChoi, Eui Young-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.alternativeNameKang, Seok Min-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNamePark, Sung Ha-
dc.contributor.alternativeNameLee, Sang Hak-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorChoi, Eui Young-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.contributor.affiliatedAuthorKang, Seok Min-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorPark, Sung Ha-
dc.contributor.affiliatedAuthorLee, Snag Hak-
dc.citation.volume20-
dc.citation.number1-
dc.citation.startPage33-
dc.citation.endPage39-
dc.identifier.bibliographicCitationCORONARY ARTERY DISEASE, Vol.20(1) : 33-39, 2009-
dc.identifier.rimsid37306-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.