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Comparative in vitro activity of tigecycline and other antimicrobials against Gram-negative and Gram-positive organisms collected from the Asia-Pacific Rim as part of the Tigecycline Evaluation and Surveillance Trial (TEST).
DC Field | Value | Language |
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dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2015-04-24T16:20:39Z | - |
dc.date.available | 2015-04-24T16:20:39Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0924-8579 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103354 | - |
dc.description.abstract | As part of the Tigecycline Evaluation and Surveillance Trial (TEST), Gram-negative and Gram-positive organisms were collected from 31 medical centres in nine countries in the Asia-Pacific Rim between 2004 and 2007. Overall, 34.2% of Acinetobacter spp. were multidrug-resistant, and 17.0% of Klebsiella pneumoniae and 10.6% of Escherichia coli produced extended-spectrum beta-lactamases. A total of 39.5% of Staphylococcus aureus were meticillin-resistant and 21.7% of Enterococcus faecium were vancomycin-resistant. Tigecycline MIC(90) values (minimum inhibitory concentration for 90% of the organisms) were <or=2mg/L against Acinetobacter spp., K. pneumoniae, E. coli, Enterobacter spp. and Serratia marcescens and <or=0.25mg/L against S. aureus, E. faecalis and Enterococcus faecium. Antimicrobial resistance is widespread in the Asia-Pacific Rim. Tigecycline has excellent in vitro activity against a broad spectrum of bacteria, including resistant strains | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 130~136 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anti-Bacterial Agents/pharmacology* | - |
dc.subject.MESH | Asia | - |
dc.subject.MESH | Drug Resistance, Multiple, Bacterial | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gram-Negative Bacteria/drug effects* | - |
dc.subject.MESH | Gram-Negative Bacteria/isolation & purification | - |
dc.subject.MESH | Gram-Negative Bacterial Infections/microbiology | - |
dc.subject.MESH | Gram-Positive Bacteria/drug effects* | - |
dc.subject.MESH | Gram-Positive Bacteria/isolation & purification | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/microbiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Methicillin Resistance | - |
dc.subject.MESH | Microbial Sensitivity Tests | - |
dc.subject.MESH | Minocycline/analogs & derivatives* | - |
dc.subject.MESH | Minocycline/pharmacology | - |
dc.subject.MESH | Oceania | - |
dc.subject.MESH | Vancomycin Resistance | - |
dc.subject.MESH | beta-Lactamases/biosynthesis | - |
dc.title | Comparative in vitro activity of tigecycline and other antimicrobials against Gram-negative and Gram-positive organisms collected from the Asia-Pacific Rim as part of the Tigecycline Evaluation and Surveillance Trial (TEST). | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Sam K. Bouchillon | - |
dc.contributor.googleauthor | Jonathan R. Iredell | - |
dc.contributor.googleauthor | Timothy Barkham | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.contributor.googleauthor | Michael J. Dowzicky | - |
dc.identifier.doi | 10.1016/j.ijantimicag.2008.07.031 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J01088 | - |
dc.identifier.eissn | 1872-7913 | - |
dc.identifier.pmid | 18995992 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0924857908003816 | - |
dc.subject.keyword | Tigecycline | - |
dc.subject.keyword | Antimicrobial resistance | - |
dc.subject.keyword | Acinetobacter | - |
dc.subject.keyword | Enterobacteriaceae | - |
dc.subject.keyword | Staphylococcus aureus | - |
dc.subject.keyword | Enterococcus faecium | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.citation.volume | 33 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 130 | - |
dc.citation.endPage | 136 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, Vol.33(2) : 130-136, 2009 | - |
dc.identifier.rimsid | 37290 | - |
dc.type.rims | ART | - |
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