돌발성 난청 환자에서 초치료로써의 고실 내 스테로이드 주입술의 치료 효과에 대한 연구Ⅱ

Abstract

Background and Objectives: Steroids are the only proven drug in the treatment for the idiopathic sudden sensorineural hearing loss (SSNHL). The intratympanic steroid injection (ITS) is thought to induce higher perilymph levels in the recent studies. However, the effect of ITS for SSNHL has not been confirmed. We studied the effectiveness of the intratympanic steroid injection for SSNHL and compared the effectiveness to other treatments as a primary treatment tool. Subjects and Methods: We reviewed the records of 226 patients seen in the past seven years from December 2002 to March 2008 who had an initial diagnosis of idiopathic SSNHL. The patients were divided into 4 groups; 78 ears treated with topical steroids (S) and heparinization (H)(Group 2), 83 ears treated with S, H and intratympanic steroid injection (ITS) (Group 3), 12 ears treated with S, H, ITS and stellate ganglion block (SGB)(Group 4), and 54 ears treated with S, H and SGB (Group 5). Results: There were no statistical differences among the treatment results of all groups. However, the theory that ITS makes the recovery of hearing earlier in the SSNHL has statistical significance. Conclusions: The results of this study suggest that ITS did not result in significant improvement of hearing, but is effective to shorten the time to reach the final hearing in the treatment of SSNHL compared to other treatments.