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The optimal phasic relationship between synchronized shock and mechanical chest compressions

Authors
 Yongqin Li  ;  Tao Yu  ;  Giuseppe Ristagno  ;  Sung Phil Chung  ;  Joe Bisera  ;  Weilun Quan  ;  Gary Freeman  ;  Max Harry Weil  ;  Wanchun Tang 
Citation
 RESUSCITATION, Vol.81(6) : 724-729, 2010 
Journal Title
 RESUSCITATION 
ISSN
 0300-9572 
Issue Date
2010
MeSH
Animals ; Cardiopulmonary Resuscitation/instrumentation* ; Cardiopulmonary Resuscitation/methods* ; Differential Threshold ; Electric Countershock/methods* ; Heart Massage/instrumentation* ; Male ; Swine ; Time Factors ; Treatment Outcome ; Ventricular Fibrillation/therapy*
Keywords
Cardiac arrest ; Ventricular fibrillation ; Defibrillation efficacy ; Upstroke phase ; Mechanical chest compression
Abstract
OBJECTIVE: Pauses for shock delivery in chest compressions are detrimental to the success of resuscitation and may be eliminated with the use of mechanical chest compressors. However, the optimal phasic relationship between mechanical chest compression and defibrillation is still unknown. We therefore undertook a study to assess the effects of timing of defibrillation in the mechanical chest compression cycle on the defibrillation threshold (DFT) using a porcine model of cardiac arrest. METHODS: Ventricular fibrillation was electrically induced and untreated for 10s in 8 domestic pigs weighing between 26 and 30 kg. Mechanical chest compression was then continuously performed for 25s, followed by a biphasic electrical shock which was delivered to the animal at 6 randomized coupling phases, including a control phase, with a pre-determined energy setting. The control phase was chosen at a constant 2s following discontinued chest compression. A novel grouped up-and-down DFT testing protocol was used to compare the success rate at different coupling phases. After a recovery interval of 4 min, the testing sequence was repeated, resulting in a total of 60 test shocks delivered to each animal. RESULTS: No difference between the delivered shock energy, voltage and current were observed among the 6 study phases. The defibrillation success rate, however, was significantly higher when shocks were delivered in the upstroke phase of mechanical chest compression. CONCLUSION: Defibrillation efficacy is maximal when electrical shock is delivered in the upstroke phase of mechanical chest compression.
Full Text
http://www.sciencedirect.com/science/article/pii/S0300957210001267
DOI
10.1016/j.resuscitation.2010.02.022
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
Yonsei Authors
Chung, Sung Pil(정성필) ORCID logo https://orcid.org/0000-0002-3074-011X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/103198
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